Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer using MED28 Polyclonal Antibody at dilution of 1/30)
Rabbit MED28 Polyclonal Antibody | anti-MED28 antibody
MED28 Polyclonal Antibody
Gene Names
MED28; EG1; magicin; 1500003D12Rik
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
MED28; Polyclonal Antibody; MED28 Polyclonal Antibody; EG1; magicin; 1500003D12Rik; anti-MED28 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
1.6mg/ml (varies by lot)
Sequence Length
178
Applicable Applications for anti-MED28 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-5000
IHC: 1:25-100
WB: 1:500-2000
IHC: 1:25-100
WB: 1:500-2000
Immunogen
Full length fusion protein
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104372
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer using MED28 Polyclonal Antibody at dilution of 1/30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer using MED28 Polyclonal Antibody at dilution of 1/30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human breast cancer using MED28 Polyclonal Antibody at dilution of 1/30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human breast cancer using MED28 Polyclonal Antibody at dilution of 1/30)
Related Product Information for anti-MED28 antibody
Med28 (mediator complex subunit 28), also known as EG1 (endothelial-derived protein 1), magicin (merlin and Grb2-interacting cytoskeletal protein) or tumor angiogenesis marker EG-1, is a 178 amino acid subunit of the Mediator complex that localizes to both nucleus and cytoplasm.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20 kDa
NCBI Official Full Name
mediator of RNA polymerase II transcription subunit 28
NCBI Official Synonym Full Names
mediator complex subunit 28
NCBI Official Symbol
MED28
NCBI Official Synonym Symbols
EG1; magicin; 1500003D12Rik
NCBI Protein Information
mediator of RNA polymerase II transcription subunit 28
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 28
Protein Family
UniProt Gene Name
MED28
UniProt Synonym Gene Names
EG1; Magicin
UniProt Entry Name
MED28_HUMAN
Uniprot Description
MED28: a component of the mediator complex that can either repress or activate transcription. Mediator complexes are essential for basal and regulated expression of nearly all RNA polymerase II-dependent genes. They may act as a bridge, conveying regulatory information from enhancers and other control elements to the promoter. May be part of a complex containing NF2/Merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. Up-regulated by endothelial cells when exposed to tumor conditioned media.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 4p16
Cellular Component: Srb-mediator complex
Molecular Function: protein binding
Research Articles on MED28
Similar Products
Product Notes
The MED28 med28 (Catalog #AAA2542546) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MED28 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MED28 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-5000 IHC: 1:25-100 WB: 1:500-2000. Researchers should empirically determine the suitability of the MED28 med28 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MED28, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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