Western Blot (WB)
(MCOLN3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MCOLN3 antibody detected the MCOLN3 protein (arrow).)
Rabbit anti-Human MCOLN3 Polyclonal Antibody | anti-MCOLN3 antibody
MCOLN3 Antibody (C-term)
Western Blot (WB)
(MCOLN3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MCOLN3 antibody detected the MCOLN3 protein (arrow).)
Western Blot (WB)
(MCOLN3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MCOLN3 antibody detected the MCOLN3 protein (arrow).)
with homologs in mouse, Drosophila, and C. elegans. Mutations in
the human MCOLN1 gene (MIM 605248) cause mucolipodosis IV (MIM
262650).
Curcio-Morelli, C., et al. J. Cell. Physiol. 222(2):328-335(2010)
Kim, H.J., et al. Traffic 10(8):1157-1167(2009)
Martina, J.A., et al. Traffic 10(8):1143-1156(2009)
Grimm, C., et al. J. Biol. Chem. 284(20):13823-13831(2009)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Uniprot Description
MCOLN3: one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Protein type: Channel, cation; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p22.3
Cellular Component: cytoplasm; integral to membrane; plasma membrane
Biological Process: locomotory behavior; auditory receptor cell differentiation; transmembrane transport
Research Articles on MCOLN3
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Product Notes
The MCOLN3 mcoln3 (Catalog #AAA9203042) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 517-546. The MCOLN3 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCOLN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MCOLN3 mcoln3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCOLN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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