Testing Data
(Gel: 8% SDS-PAGELane1: Hela cell lysateLane2: 293T cell lysateLysates: 40ug per lanePrimary antibody: 1/1300 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/5000 dilutionExposure time: 2 minutes)
Rabbit anti-Human MCMBP Polyclonal Antibody | anti-MCMBP antibody
MCMBP Antibody
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Testing Data
(Gel: 8% SDS-PAGELane1: Hela cell lysateLane2: 293T cell lysateLysates: 40ug per lanePrimary antibody: 1/1300 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/5000 dilutionExposure time: 2 minutes)
Testing Data
(Gel: 8% SDS-PAGELane1: Hela cell lysateLane2: 293T cell lysateLysates: 40ug per lanePrimary antibody: 1/1300 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/5000 dilutionExposure time: 2 minutes)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 31234(MCMBP Antibody) at dilution 1/60, on the right is treated with the synthetic peptide.)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 31234(MCMBP Antibody) at dilution 1/60, on the right is treated with the synthetic peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which is a component of the hexameric minichromosome maintenance (MCM) complex which regulates initiation and elongation of DNA. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Uniprot Description
MCMBP: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. Belongs to the MCMBP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 10q26.11
Cellular Component: nucleoplasm; MCM complex; cytoplasm; plasma membrane; nucleus
Molecular Function: protein binding; chromatin binding
Biological Process: mitosis; cell division; sister chromatid cohesion; DNA-dependent DNA replication
Research Articles on MCMBP
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Product Notes
The MCMBP mcmbp (Catalog #AAA9407440) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCMBP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCMBP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the MCMBP mcmbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCMBP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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