Rabbit anti-Human MCCC2 Polyclonal Antibody | anti-MCCC2 antibody

MCCC2, CT (MCCC2, MCCB, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, 3-methylcrotonyl-CoA carboxylase 2, 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (FITC)

Cat. Num. AAA6319587

• Gene Names: MCCC2; MCCB
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MCCC2; Polyclonal Antibody; CT (MCCC2; MCCB; Methylcrotonoyl-CoA carboxylase beta chain; mitochondrial; 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (FITC); 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; anti-MCCC2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-MCCC2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: MCCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 468-496 amino acids from the C-terminal region of human MCCC2.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MCCC2 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MCCC2 antibody detected the MCCC2 protein (arrow).)

Related Product Information for anti-MCCC2 antibody

This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Product Categories/Family for anti-MCCC2 antibody

Antibodies; Mitochondrial Proteins

References

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010). Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010). Cho, Y.S., et al. Proteins 70(1):268-272(2008). Uematsu, M., et al. J. Hum. Genet. 52(12):1040-1043(2007). Stadler, S.C., et al. Biochem. Biophys. Res. Commun. 334(3):939-946(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 11545863
• NCBI GeneID: 64087
• NCBI Accession #: NP_071415.1
• NCBI GenBank Nucleotide #: NM_022132.4
• UniProt Accession #: Q9HCC0; Q96C27; Q9Y4L7; A6NIY9
• Molecular Weight: 57,519 Da
• NCBI Official Full Name: methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
• NCBI Official Synonym Full Names: methylcrotonoyl-CoA carboxylase 2 (beta)
• NCBI Official Symbol: MCCC2
• NCBI Official Synonym Symbols: MCCB
• NCBI Protein Information: methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; MCCase subunit beta; biotin carboxylase
• UniProt Protein Name: Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
• Protein Family: Methylcrotonoyl-CoA carboxylase
• UniProt Gene Name: MCCC2
• UniProt Synonym Gene Names: MCCB; MCCase subunit beta
• UniProt Entry Name: MCCB_HUMAN