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Western Blot (WB) (WB Suggested Anti-MAPKBP1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Stomach)

Rabbit MAPKBP1 Polyclonal Antibody | anti-MAPKBP1 antibody

MAPKBP1 antibody - N-terminal region

Gene Names
MAPKBP1; JNKBP1; NPHP20; JNKBP-1
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applications
Western Blot
Purity
Affinity Purified
Synonyms
MAPKBP1; Polyclonal Antibody; MAPKBP1 antibody - N-terminal region; anti-MAPKBP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: MAVEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGITVS
Sequence Length
1508
Applicable Applications for anti-MAPKBP1 antibody
Western Blot (WB)
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MAPKBP1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(WB Suggested Anti-MAPKBP1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Stomach)

Western Blot (WB) (WB Suggested Anti-MAPKBP1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Stomach)
Related Product Information for anti-MAPKBP1 antibody
This is a rabbit polyclonal antibody against MAPKBP1. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: MAPKBP1 is involved in JNK signaling pathway.
Product Categories/Family for anti-MAPKBP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
163kDa
NCBI Official Full Name
mitogen-activated protein kinase-binding protein 1 isoform a
NCBI Official Synonym Full Names
mitogen-activated protein kinase binding protein 1
NCBI Official Symbol
MAPKBP1
NCBI Official Synonym Symbols
JNKBP1; NPHP20; JNKBP-1
NCBI Protein Information
mitogen-activated protein kinase-binding protein 1
UniProt Protein Name
Mitogen-activated protein kinase-binding protein 1
UniProt Gene Name
MAPKBP1
UniProt Synonym Gene Names
JNKBP1; KIAA0596; JNKBP-1
UniProt Entry Name
MABP1_HUMAN

NCBI Description

This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. [provided by RefSeq, May 2017]

Uniprot Description

MAPKBP1: Involved in JNK signaling pathway. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q15.1

Research Articles on MAPKBP1

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Product Notes

The MAPKBP1 mapkbp1 (Catalog #AAA3212073) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAPKBP1 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAPKBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the MAPKBP1 mapkbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: MAVEGSTITS RIKNLLRSPS IKLRRSKAGN RREDLSSKVT LEKVLGITVS. It is sometimes possible for the material contained within the vial of "MAPKBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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