Western Blot (WB)
(Western blot of human T47D cells showing specific immunolabeling of ~45k MEK 1 (Control))
Rabbit MAP2K1 Polyclonal Antibody | anti-MAP2K1 antibody
MAP2K1 antibody (Thr386)
Applications
Western Blot
Purity
MAP2K1 antibody was purified by affinity chromatography
Synonyms
MAP2K1; Polyclonal Antibody; MAP2K1 antibody (Thr386); Polyclonal MAP2K1; Anti-MAP2K1; MAP2K 1; MAP2K-1; Mitogen-activated protein kinase kinase 1; MEK1; PRKMK1; ERK activator kinase 1; MAP kinase kinase 1; anti-MAP2K1 antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
MAP2K1 antibody was purified by affinity chromatography
Form/Format
Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol
Sequence Length
393
Applicable Applications for anti-MAP2K1 antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Biological Significance
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade.
Western Blot (WB)
(Western blot of human T47D cells showing specific immunolabeling of ~45k MEK 1 (Control))
Western Blot (WB)
(Western blot of human T47D cells showing specific immunolabeling of ~45k MEK 1 (Control))
Related Product Information for anti-MAP2K1 antibody
Rabbit polyclonal MAP2K1 antibody (Thr386)
Product Categories/Family for anti-MAP2K1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
43,439 Da
NCBI Official Full Name
MAP2K1 protein
NCBI Official Symbol
MAP2K1
NCBI Protein Information
dual specificity mitogen-activated protein kinase kinase 1
UniProt Protein Name
MAP2K1 protein
UniProt Gene Name
MAP2K1
UniProt Entry Name
Q0VD16_BOVIN
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Product Notes
The MAP2K1 map2k1 (Catalog #AAA837308) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MAP2K1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the MAP2K1 map2k1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAP2K1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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