Western Blot (WB)
(Mouse Map2k1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Map2k1 antibody detected the Map2k1 protein (arrow).)
Rabbit Map2k1 Polyclonal Antibody | anti-Map2k1 antibody
Mouse Map2k1 Antibody (C-term)
Western Blot (WB)
(Mouse Map2k1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Map2k1 antibody detected the Map2k1 protein (arrow).)
Western Blot (WB)
(Mouse Map2k1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Map2k1 antibody detected the Map2k1 protein (arrow).)
Western Blot (WB)
(Western blot analysis of Map2k1 (arrow) using rabbit polyclonal Mouse Map2k1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Map2k1 gene.)
Western Blot (WB)
(Western blot analysis of Map2k1 (arrow) using rabbit polyclonal Mouse Map2k1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Map2k1 gene.)
Western Blot (WB)
(Mouse Map2k1 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Map2k1 antibody detected the Map2k1 protein (arrow).)
Western Blot (WB)
(Mouse Map2k1 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Map2k1 antibody detected the Map2k1 protein (arrow).)
Immunohistochemistry (IHC)
(Mouse Map2k1 Antibody (C-term) (MBS9206857)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Map2k1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse Map2k1 Antibody (C-term) (MBS9206857)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Map2k1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Yang, T., et al. J. Clin. Invest. 120(7):2474-2485(2010)
Cho, K.W., et al. J. Exp. Zool. B Mol. Dev. Evol. 312(8):901-911(2009)
Jo, C., et al. Cell. Signal. 21(12):1910-1917(2009)
Mandal, M., et al. Nat. Immunol. 10(10):1110-1117(2009)
NCBI and Uniprot Product Information
Uniprot Description
MEK1: a dual-specificity protein kinase of the STE7 kinase family. Phosphorylated and activated by Raf, Mos and Cot kinases. Phosphorylates a Thr and a Tyr residue in a Thr-Glu-Tyr sequence located in the activation loop of ERK1 and ERK2. An essential component of MAP kinase signal transduction pathways involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Protein type: EC 2.7.12.2; Protein kinase, STE; Kinase, protein; Protein kinase, dual-specificity (non-receptor); STE group; STE7 family
Cellular Component: dendrite cytoplasm; Golgi apparatus; microtubule; focal adhesion; mitochondrion; endoplasmic reticulum; dendrite; early endosome; perikaryon; cell cortex; cytosol; cytoskeleton; perinuclear region of cytoplasm; axon; late endosome; cytoplasm; plasma membrane; nucleus
Molecular Function: protein C-terminus binding; nucleotide binding; protein N-terminus binding; mitogen-activated protein kinase kinase kinase binding; protein kinase binding; protein kinase activity; MAP kinase kinase activity; transferase activity; protein serine/threonine kinase activator activity; protein serine/threonine kinase activity; protein binding; Ras GTPase binding; receptor signaling protein tyrosine phosphatase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; protein serine/threonine/tyrosine kinase activity; kinase activity; ATP binding
Biological Process: activation of MAPK activity; protein heterooligomerization; negative regulation of homotypic cell-cell adhesion; response to glucocorticoid stimulus; cell motility involved in cell locomotion; protein amino acid phosphorylation; neuron differentiation; negative regulation of cell proliferation; positive regulation of RNA elongation from RNA polymerase II promoter; vesicle transport along microtubule; response to axon injury; cell cycle arrest; Golgi inheritance; mitosis; MAPKKK cascade; melanosome transport; keratinocyte differentiation; regulation of axon regeneration; cell proliferation; regulation of stress-activated MAPK cascade; regulation of vascular smooth muscle contraction; positive regulation of axonogenesis; positive regulation of Ras protein signal transduction; response to oxidative stress; positive regulation of cell differentiation; phosphorylation; neurite morphogenesis; positive regulation of cell migration
Research Articles on Map2k1
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Product Notes
The Map2k1 map2k1 (Catalog #AAA9206857) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 269-296. The Mouse Map2k1 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Hamster, Rabbit, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Map2k1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Map2k1 map2k1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Map2k1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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