Rabbit anti-Human, Mouse Map2 Polyclonal Antibody | anti-Map2 antibody

Map2 Antibody

Cat. Num. AAA9407826

• Gene Names: Map2; MAP-2; Mtap2; Mtap-2; repro4; G1-397-34
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Synonyms: Map2; Polyclonal Antibody; Map2 Antibody; microtubule-associated protein 2; MAP2A; MAP2B; MAP2C; anti-Map2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total Map2 protein.
• Form/Format: Supplied at 1.4mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
• Sequence Length: 1828

• Applicable Applications for anti-Map2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: ELISA: 1:1000-1:5000; Western blotting: 1:200-1:1000; Immunohistochemistry: 1:50-1:200
• Immunogen Type: Peptide-KLH
• Immunogen Description: Synthetic peptide corresponding to a region derived from 32~45 amino acids of mouse microtubule-associated protein 2
• Target Name: Map2
• Preparation and Storage: Store at -20 degree C/1 year

Testing Data

(Gel: 8%+10%+12%%SDS-PAGE Lysate: 50 ug Human lymphoma tissue lysate Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 90 seconds)

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using 31273 (Map2 Antibody) at dilution 1/40, on the right is treated with the synthetic peptide.)

Related Product Information for anti-Map2 antibody

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.

Product Categories/Family for anti-Map2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 568905901
• NCBI GeneID: 17756
• NCBI Accession #: XP_006495817.1
• NCBI GenBank Nucleotide #: XM_006495754.2
• UniProt Accession #: P20357; E9QLE1
• Molecular Weight: 199,132 Da
• NCBI Official Full Name: microtubule-associated protein 2 isoform X10
• NCBI Official Synonym Full Names: microtubule-associated protein 2
• NCBI Official Symbol: Map2
• NCBI Official Synonym Symbols: MAP-2; Mtap2; Mtap-2; repro4; G1-397-34
• NCBI Protein Information: microtubule-associated protein 2
• UniProt Protein Name: Microtubule-associated protein 2
• Protein Family: Microtubule-associated protein
• UniProt Gene Name: Map2
• UniProt Synonym Gene Names: Mtap2; MAP-2
• UniProt Entry Name: MTAP2_MOUSE

Uniprot Description

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Cellular Component: microtubule; neuron projection; smooth endoplasmic reticulum; protein complex; rough endoplasmic reticulum; dendrite; postsynaptic density; microtubule associated complex; cytoskeleton; cell soma; cytoplasm; nucleolus; dendritic shaft; intracellular

Molecular Function: calmodulin binding; tubulin binding; protein binding; microtubule binding; cytoskeletal regulatory protein binding

Biological Process: axonogenesis; dendrite development; microtubule bundle formation