Western Blot (WB)
(Western Blot analysis of CLPB expression in transfected 293T cell line by CLPB polyclonal antibody. Lane 1: CLPB transfected lysate (78.7kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human CLPB Polyclonal Antibody | anti-CLPB antibody
CLPB (Caseinolytic Peptidase B Protein Homolog, Suppressor of Potassium Transport Defect 3, HSP78, SKD3, FLJ13152) APC
Gene Names
CLPB; SKD3; HSP78; MGCA7; ANKCLB; MEGCANN
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CLPB; Polyclonal Antibody; CLPB (Caseinolytic Peptidase B Protein Homolog; Suppressor of Potassium Transport Defect 3; HSP78; SKD3; FLJ13152) APC; anti-CLPB antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CLPB.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-CLPB antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human CLPB, aa1-707 (NP_110440.1).
Immunogen Sequence
MLGSLVLRRKALAPRLLLRLLRSPTLRGHGGASGRNVTTGSLGEPQWLRVATGGRPGTSPALFSGRGAATGGRQGGRFDTKCLAAATWGRLPGPEETLPGQDSWNGVPSRAGLGMCALAAALVVHCYSKSPSNKDAALLEAARANNMQEVSRLLSEGADVNAKHRLGWTALMVAAINRNNSVVQVLLAAGADPNLGDDFSSVYKTAKEQGIHSLEDGGQDGASRHITNQWTSALEFRRWLGLPAGVLITREDDFNNRLNNRASFKGCTALHYAVLADDYRTVKELLDGGANPLQRNEMGHTPLDYAREGEVMKLLRTSEAKYQEKQRKREAEERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKLRLEIIDKDSKTRRLDIRAPLHPEKVCNTI
Conjugate
APC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of CLPB expression in transfected 293T cell line by CLPB polyclonal antibody. Lane 1: CLPB transfected lysate (78.7kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CLPB expression in transfected 293T cell line by CLPB polyclonal antibody. Lane 1: CLPB transfected lysate (78.7kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-CLPB antibody
CLPB may function as a regulatory ATPase and be related to secretion/protein trafficking process.
Product Categories/Family for anti-CLPB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,664 Da
NCBI Official Full Name
caseinolytic peptidase B protein homolog isoform 1
NCBI Official Synonym Full Names
ClpB homolog, mitochondrial AAA ATPase chaperonin
NCBI Official Symbol
CLPB
NCBI Official Synonym Symbols
SKD3; HSP78; MGCA7; ANKCLB; MEGCANN
NCBI Protein Information
caseinolytic peptidase B protein homolog
Protein Family
NCBI Description
This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Research Articles on CLPB
Similar Products
Product Notes
The CLPB (Catalog #AAA6374160) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLPB (Caseinolytic Peptidase B Protein Homolog, Suppressor of Potassium Transport Defect 3, HSP78, SKD3, FLJ13152) APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLPB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CLPB for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLPB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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