Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at RT. The detected MAP1LC3 C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Rabbit anti-Human MAP1LC3C Polyclonal Antibody | anti-MAP1LC3C antibody
MAP1LC3C (Microtubule Associated Proteins 1A/1B Light Chain 3C, Autophagy Related Protein LC3C, Autophagy Related Ubiquitin-like Modifier LC3C, LC3C, LC3-like Protein 2, MAP1 Light Chain 3-like Protein 2, MAP1 Light Chain 3-like Protein 3, MAP1A/MAP1BLC3C
Serum
Serum
Dilution: Immunohistochemistry: 1:100-1:1000
Western Blot: 1:100-1:1000
Immunofluorescence: 1:100-1:1000
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at RT. The detected MAP1LC3 C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at RT. The detected MAP1LC3 C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at room temperature. The detected MAP1LC3C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at room temperature. The detected MAP1LC3C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at room temperature. The detected MAP1LC3C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at room temperature. The detected MAP1LC3C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at room temperature. The detected MAP1LC3C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Immunofluorescence (IF)
(Confocal microscopy on immunofluorescently detected MAP1LC3C in cytospin-isolated human white blood cells using MBS616757 at a dilution of 1: 200, incubated for 1 h at room temperature. The detected MAP1LC3C appears red. The cells were also stained for Myeloperoxidase (MPO) appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.)
Western Blot (WB)
(Western blot (reducing condition analysis of 293 cell lysate using MBS616757 at a dilution of 1:100.)
Western Blot (WB)
(Western blot (reducing condition analysis of 293 cell lysate using MBS616757 at a dilution of 1:100.)
NCBI and Uniprot Product Information
NCBI Description
Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).[supplied by OMIM]
Uniprot Description
LC3C: is a ubiquitin-like protein that is a constituent of the ATG8-conjugation system, one of two evolutionarily conserved phosphatidylethanolamine conjugation systems necessary for the formation of the autophagosome. The human ATG8 system includes seven ubiquitin-like light chain proteins (LCPs) that are homologs of yeast LC3: MAP1LC3A, -B, -C, GABARAP, GABARAPL1, -2, and -3. Pro-LCPs are cleaved by ATG4B to expose a C-terminal glycine residue, the cytosolic LCP-I form. The exposed C-terminus is conjugated to the head group amine of phosphatidylethanolamine (PE) through an amide bond by a sequence of ubiquitination-like reactions that involves an E1 (ATG7), an E2 (ATG3), and an E3 (a complex including ATG5, ATG12, and ATG16L). The PE-congugated form (LCP-II) is tightly associated with the autophagosomal membrane. The LCP-II forms can also be delipidated by the ATG4 proteases: most of the LCPs are delipidated and liberated from the membrane before autophagosomes fuse with lysosomes.
Protein type: Vesicle; Ubiquitin-like modifier; Microtubule-binding; Autophagy
Chromosomal Location of Human Ortholog: 1q43
Cellular Component: microtubule; extrinsic to membrane; endomembrane system; autophagic vacuole; cytoplasmic vesicle; cytosol
Molecular Function: protein binding; microtubule binding; GABA receptor binding
Biological Process: mitochondrion degradation; cellular response to nitrogen starvation; autophagic vacuole formation
Similar Products
Product Notes
The MAP1LC3C map1lc3c (Catalog #AAA616757) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAP1LC3C (Microtubule Associated Proteins 1A/1B Light Chain 3C, Autophagy Related Protein LC3C, Autophagy Related Ubiquitin-like Modifier LC3C, LC3C, LC3-like Protein 2, MAP1 Light Chain 3-like Protein 2, MAP1 Light Chain 3-like Protein 3, MAP1A/MAP1BLC3C reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAP1LC3C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Dilution: Immunohistochemistry: 1:100-1:1000 Western Blot: 1:100-1:1000 Immunofluorescence: 1:100-1:1000. Researchers should empirically determine the suitability of the MAP1LC3C map1lc3c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAP1LC3C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
