Rabbit MAP17 Polyclonal Antibody | anti-PDZK1IP1 antibody
MAP17 (17kD Membrane-associated Protein, DD96, PDZK1-interacting Protein 1, Pdzk1ip1, SPAP)
Gene Names
PDZK1IP1; DD96; SPAP; MAP17; RP1-18D14.5; PDZK1IP1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
SerumSerum
Synonyms
MAP17; Polyclonal Antibody; MAP17 (17kD Membrane-associated Protein; DD96; PDZK1-interacting Protein 1; Pdzk1ip1; SPAP); Anti -MAP17 (17kD Membrane-associated Protein; anti-PDZK1IP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
This antibody is specific for MAP17. Species Crossreactivity: Mouse, human, and rat.
Purity/Purification
Serum
Serum
Serum
Applicable Applications for anti-PDZK1IP1 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
A synthetic peptide made to the C-terminus of mouse MAP17.
Cellular Localization
Membrane-associated
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-PDZK1IP1 antibody
The small PDZK1-associated protein (SPAP; also known as MAP17) is an endogenous regulator of cellular PDZK1 levels by regulating PDZK1 turnover.
Product Categories/Family for anti-PDZK1IP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
12,227 Da
NCBI Official Full Name
MAP17
NCBI Official Synonym Full Names
PDZK1 interacting protein 1
NCBI Official Symbol
PDZK1IP1
NCBI Official Synonym Symbols
DD96; SPAP; MAP17; RP1-18D14.5; PDZK1IP1
NCBI Protein Information
PDZK1-interacting protein 1; OTTHUMP00000009573; membrane-associated protein 17; 17 kDa membrane-associated protein; epithelial protein up-regulated in carcinoma, membrane associated protein 17
UniProt Protein Name
PDZK1-interacting protein 1
Protein Family
UniProt Gene Name
PDZK1IP1
UniProt Synonym Gene Names
MAP17
UniProt Entry Name
PDZ1I_HUMAN
Uniprot Description
PDZK1IP1: May play an important role in tumor biology.
Protein type: Membrane protein, integral; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1p33
Cellular Component: integral to membrane
Research Articles on PDZK1IP1
1. point mutation observed by transcriptome sequencing of malignant pleural mesothelioma tumors
2. MAP17 protein activates AKT through ROS and this is determinant to confer resistance to Myc-induced apoptosis in the absence of serum.
3. Tumorigenic capability of MAP17 through a connection between sodium-coupled co-transporters and reactive oxygen species.
4. Independent activation of MAP17 promoter can be driven by oncogenes and might explain the common overexpression of MAP17 in human carcinomas.
5. Large scale genetic screening identifies MAP17 as protein bypassing TNF-alpha-induced growth arrest.
2. MAP17 protein activates AKT through ROS and this is determinant to confer resistance to Myc-induced apoptosis in the absence of serum.
3. Tumorigenic capability of MAP17 through a connection between sodium-coupled co-transporters and reactive oxygen species.
4. Independent activation of MAP17 promoter can be driven by oncogenes and might explain the common overexpression of MAP17 in human carcinomas.
5. Large scale genetic screening identifies MAP17 as protein bypassing TNF-alpha-induced growth arrest.
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Product Notes
The PDZK1IP1 pdzk1ip1 (Catalog #AAA613508) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAP17 (17kD Membrane-associated Protein, DD96, PDZK1-interacting Protein 1, Pdzk1ip1, SPAP) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAP17 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the PDZK1IP1 pdzk1ip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAP17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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