Immunohistochemistry (IHC)
(Anti-Alpha-Mannosidase II / MAN2A2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Mouse, Human MAN2A2 / Alpha-Mannosidase II Polyclonal Antibody | anti-MAN2A2 antibody
Anti-MAN2A2 / Alpha-Mannosidase II Antibody (aa766-796) IHC-plus
IHC-P (5 ug/ml)
WB (1:1000)
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Immunohistochemistry (IHC)
(Anti-Alpha-Mannosidase II / MAN2A2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-Alpha-Mannosidase II / MAN2A2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Western Blot (WB)
(MAN2A2 Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The MAN2A2 antibody detected the MAN2A2 protein (arrow).)
Western Blot (WB)
(MAN2A2 Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The MAN2A2 antibody detected the MAN2A2 protein (arrow).)
Flow Cytometry (FC/FACS)
(MAN2A2 Antibody flow cytometry of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(MAN2A2 Antibody flow cytometry of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
Uniprot Description
MAN2A2: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. Belongs to the glycosyl hydrolase 38 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.2.1.114; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Hydrolase
Chromosomal Location of Human Ortholog: 15q26.1
Cellular Component: Golgi membrane; integral to membrane
Molecular Function: alpha-mannosidase activity; carbohydrate binding; hydrolase activity, hydrolyzing N-glycosyl compounds; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; zinc ion binding
Biological Process: cellular protein metabolic process; mannose metabolic process; N-glycan processing; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; protein deglycosylation
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Product Notes
The MAN2A2 man2a2 (Catalog #AAA249809) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MAN2A2 / Alpha-Mannosidase II Antibody (aa766-796) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAN2A2 / Alpha-Mannosidase II can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS). Flow Cytometry (1:10 - 1:50) IHC-P (5 ug/ml) WB (1:1000). Researchers should empirically determine the suitability of the MAN2A2 man2a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAN2A2 / Alpha-Mannosidase II, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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