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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MAL Polyclonal Antibody at dilution 1:30)

Rabbit MAL Polyclonal Antibody | anti-MAL antibody

MAL Polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
MAL; Polyclonal Antibody; MAL Polyclonal Antibody; anti-MAL antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.8mg/mL (varies by lot)
Sequence Length
153
Applicable Applications for anti-MAL antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human MAL
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MAL Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MAL Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human brain tissue using MAL Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human brain tissue using MAL Polyclonal Antibody at dilution 1:30)
Related Product Information for anti-MAL antibody
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
Product Categories/Family for anti-MAL antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
5,989 Da
NCBI Official Full Name
MAL
UniProt Protein Name
Myelin and lymphocyte protein
Protein Family
UniProt Gene Name
MAL
UniProt Entry Name
MAL_HUMAN

Uniprot Description

MAL: Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function. Belongs to the MAL family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q11.1

Cellular Component: extrinsic to membrane; integral to plasma membrane; endoplasmic reticulum; apical plasma membrane; endosome; lipid raft

Molecular Function: protein binding; structural constituent of myelin sheath; channel activity; apoptotic protease activator activity; lipid binding

Biological Process: myelination; apical protein localization; central nervous system development; apoptosis; cell differentiation; lipid raft polarization; transmembrane transport

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Product Notes

The MAL mal (Catalog #AAA2527140) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAL Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the MAL mal for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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