Rabbit anti-Human MAGI2 Polyclonal Antibody | anti-MAGI2 antibody

MAGI2 Antibody

Cat. Num. AAA7105309

• Gene Names: MAGI2; AIP1; AIP-1; ARIP1; SSCAM; MAGI-2; ACVRIP1
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Immunofluorescence
• Purity: >95%, Protein G purified
• Synonyms: MAGI2; Polyclonal Antibody; MAGI2 Antibody; Membrane-associated guanylate kinase; WW and PDZ domain-containing protein 2; Atrophin-1-interacting protein 1; AIP-1; Atrophin-1-interacting protein A; Membrane-associated guanylate kinase inverted 2; MAGI-2; ACVRINP1; AIP1; KIAA0705; anti-MAGI2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 1441

• Applicable Applications for anti-MAGI2 antibody: ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: IHC: 1:20-1:200; IF: 1:50-1:200
• Immunogen: Recombinant Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 protein (1308-1455AA)
• Conjugation: Non-conjugated
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7105309 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of A549 cells using MBS7105309 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-MAGI2 antibody

Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.

Product Categories/Family for anti-MAGI2 antibody

Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 667477958
• NCBI GeneID: 9863
• NCBI Accession #: NP_001288057.1
• NCBI GenBank Nucleotide #: NM_001301128.1
• UniProt Accession #: Q86UL8; O60434; O60510; Q86UI7; Q9NP44; Q9UDQ5; Q9UDU1; A4D1C1; A7E2C3
• Molecular Weight: 157,236 Da
• NCBI Official Full Name: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform 2
• NCBI Official Synonym Full Names: membrane associated guanylate kinase, WW and PDZ domain containing 2
• NCBI Official Symbol: MAGI2
• NCBI Official Synonym Symbols: AIP1; AIP-1; ARIP1; SSCAM; MAGI-2; ACVRIP1
• NCBI Protein Information: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
• UniProt Protein Name: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
• Protein Family: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein
• UniProt Gene Name: MAGI2
• UniProt Synonym Gene Names: ACVRINP1; AIP1; KIAA0705; AIP-1; MAGI-2

NCBI Description

The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]

Uniprot Description

Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.