Western Blot (WB)
(WB Suggested Anti-MAD2L1BP AntibodyTitration: 1.0 ug/mlPositive Control: MDA-MB-435S Whole CellMAD2L1BP is supported by BioGPS gene expression data to be expressed in MDA-MB435)
Rabbit MAD2L1BP Polyclonal Antibody | anti-MAD2L1BP antibody
MAD2L1BP antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-MAD2L1BP AntibodyTitration: 1.0 ug/mlPositive Control: MDA-MB-435S Whole CellMAD2L1BP is supported by BioGPS gene expression data to be expressed in MDA-MB435)
Western Blot (WB)
(WB Suggested Anti-MAD2L1BP AntibodyTitration: 1.0 ug/mlPositive Control: MDA-MB-435S Whole CellMAD2L1BP is supported by BioGPS gene expression data to be expressed in MDA-MB435)
Target Description: The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Uniprot Description
MAD2L1BP: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. Belongs to the MAD2L1BP family.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleolus; spindle; nucleus
Molecular Function: protein binding
Biological Process: mitotic cell cycle checkpoint; regulation of exit from mitosis
Research Articles on MAD2L1BP
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Product Notes
The MAD2L1BP mad2l1bp (Catalog #AAA3215197) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAD2L1BP antibody - N-terminal region reacts with Dog, Horse, Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's MAD2L1BP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the MAD2L1BP mad2l1bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: SAAVPDLEWY EKSEETHASQ IELLETSSTQ EPLNASEAFC PRDCMVPVVF. It is sometimes possible for the material contained within the vial of "MAD2L1BP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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