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Western Blot (WB) (Western blot analysis of M11D1 Antibody (N-term) in HL-60 cell line lysates (35ug/lane). M11D1 (arrow) was detected using the purified Pab.)

Rabbit anti-Human M11D1 Polyclonal Antibody | anti-METTL17 antibody

M11D1 Antibody (N-term)

Gene Names
METTL17; METT11D1
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
M11D1; Polyclonal Antibody; M11D1 Antibody (N-term); Methyltransferase-like protein 17; mitochondrial; 211-; False p73 target gene protein; Methyltransferase 11 domain-containing protein 1; Protein RSM22 homolog; METTL17; METT11D1; anti-METTL17 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This M11D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human M11D1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
88-116
Sequence Length
478
Applicable Applications for anti-METTL17 antibody
Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of M11D1 Antibody (N-term) in HL-60 cell line lysates (35ug/lane). M11D1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of M11D1 Antibody (N-term) in HL-60 cell line lysates (35ug/lane). M11D1 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(M11D1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the M11D1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (M11D1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the M11D1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(M11D1 Antibody (N-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (M11D1 Antibody (N-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-METTL17 antibody
M11D1 may be a component of the mitochondrial small ribosomal subunit.
References
Lim, J., et al. Cell 125(4):801-814(2006)
Saveanu, C., et al. J. Biol. Chem. 276(19):15861-15867(2001)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50734
NCBI Official Full Name
methyltransferase-like protein 17, mitochondrial isoform 1
NCBI Official Synonym Full Names
methyltransferase like 17
NCBI Official Symbol
METTL17
NCBI Official Synonym Symbols
METT11D1
NCBI Protein Information
methyltransferase-like protein 17, mitochondrial
UniProt Protein Name
Methyltransferase-like protein 17, mitochondrial
UniProt Gene Name
METTL17
UniProt Synonym Gene Names
METT11D1
UniProt Entry Name
MET17_HUMAN

Uniprot Description

METT11D1: May be a component of the mitochondrial small ribosomal subunit. Belongs to the methyltransferase superfamily. Rsm22 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.1.1.-; Methyltransferase

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm; mitochondrion; ribosome; nucleus

Molecular Function: methyltransferase activity; protein binding; copper ion binding

Biological Process: methylation; translation

Research Articles on METTL17

Similar Products

Product Notes

The METTL17 mettl17 (Catalog #AAA9214606) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 88-116. The M11D1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's M11D1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the METTL17 mettl17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M11D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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