Western Blot (WB)
(Western blot analysis of lysates from mouse cerebellum,human cerebellum tissue lysate (from left to right), using Cckar Antibody (C-term) MBS9231693. It was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.)
Rabbit M Cckar Polyclonal Antibody | anti-Cckar antibody
M Cckar Antibody (C-term)
Gene Names
Cckar; AW106902
Reactivity
Human, MousePredicted: Rat
Applications
Western Blot, ELISA
Synonyms
M Cckar; Polyclonal Antibody; M Cckar Antibody (C-term); Cckar; Cholecystokinin receptor type A; anti-Cckar antibody
Host
Rabbit
Reactivity
Human, Mouse
Predicted: Rat
Predicted: Rat
Clonality
Polyclonal
Isotype
Ig
Specificity
This Mouse Cckar antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse Cckar.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
436
Applicable Applications for anti-Cckar antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000
Antigen Source
Mouse
Antigen Region
325-356
Antigen Type
Synthetic Peptide
Function
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Cellular Location
Cell membrane; Multi-pass membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Western blot analysis of lysates from mouse cerebellum,human cerebellum tissue lysate (from left to right), using Cckar Antibody (C-term) MBS9231693. It was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.)
Western Blot (WB)
(Western blot analysis of lysates from mouse cerebellum,human cerebellum tissue lysate (from left to right), using Cckar Antibody (C-term) MBS9231693. It was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.)
Related Product Information for anti-Cckar antibody
Description: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Background: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Background: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
References
Takata Y., et al. Gene 187:267-271(1997). Lacourse K.A., et al. Biochem. Biophys. Res. Commun. 236:630-635(1997). Carninci P., et al. Science 309:1559-1563(2005).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: Mouse: 48, Rat: 50 KdA
NCBI Official Full Name
cholecystokinin receptor type A isoform 1
NCBI Official Synonym Full Names
cholecystokinin A receptor
NCBI Official Symbol
Cckar
NCBI Official Synonym Symbols
AW106902
NCBI Protein Information
cholecystokinin receptor type A
UniProt Protein Name
Cholecystokinin receptor type A
Protein Family
UniProt Gene Name
Cckar
UniProt Synonym Gene Names
CCK-A receptor; CCK-AR; CCK1-R
Uniprot Description
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system ().
Research Articles on Cckar
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Product Notes
The Cckar cckar (Catalog #AAA9231693) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The M Cckar Antibody (C-term) reacts with Human, Mouse Predicted: Rat and may cross-react with other species as described in the data sheet. AAA Biotech's M Cckar can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000. Researchers should empirically determine the suitability of the Cckar cckar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M Cckar, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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