Western Blot (WB)
(Western blot analysis of LZTR2 in mouse kidney tissue lysate with LZTR2 antibody at 1 μg/mL.)
Rabbit LZTR2 Polyclonal Antibody | anti-SEC16B antibody
LZTR2 Antibody
Gene Names
SEC16B; RGPR; LZTR2; SEC16S; PGPR-p117
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
LZTR2 Antibody is affinity chromatography purified via peptide column.
Synonyms
LZTR2; Polyclonal Antibody; LZTR2 Antibody; RGPR; SEC16S; PGPR-p117; KIAA1928; Protein transport protein Sec16B; Leucine zipper transcription regulator 2; RGPR-p117; SEC16 homolog B (S. cerevisiae); anti-SEC16B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
LZTR2 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1060
Applicable Applications for anti-SEC16B antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
LZTR2 antibody can be used for detection of LZTR2 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
LZTR2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LZTR2.
Buffer
LZTR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
LZTR2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of LZTR2 in mouse kidney tissue lysate with LZTR2 antibody at 1 μg/mL.)
Western Blot (WB)
(Western blot analysis of LZTR2 in mouse kidney tissue lysate with LZTR2 antibody at 1 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of LZTR2 in mouse kidney tissue with LZTR2 antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of LZTR2 in mouse kidney tissue with LZTR2 antibody at 5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of LZTR2 in mouse kidney tissue with LZTR2 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of LZTR2 in mouse kidney tissue with LZTR2 antibody at 20 μg/mL.)
Related Product Information for anti-SEC16B antibody
LZTR2 Antibody: LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,124 Da
NCBI Official Full Name
protein transport protein Sec16B
NCBI Official Synonym Full Names
SEC16 homolog B (S. cerevisiae)
NCBI Official Symbol
SEC16B
NCBI Official Synonym Symbols
RGPR; LZTR2; SEC16S; PGPR-p117
NCBI Protein Information
protein transport protein Sec16B; RGPR-p117; protein SEC16 homolog B; leucine zipper transcription regulator 2; regucalcin gene promotor region related protein; regucalcin gene promoter region-related protein p117
UniProt Protein Name
Protein transport protein Sec16B
Protein Family
UniProt Gene Name
SEC16B
UniProt Synonym Gene Names
KIAA1928; LZTR2; RGPR; SEC16S; RGPR-p117
UniProt Entry Name
SC16B_HUMAN
NCBI Description
SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009]
Uniprot Description
SEC16B: Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization. Belongs to the SEC16 family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 1q25.2
Cellular Component: Golgi membrane; endoplasmic reticulum membrane; intracellular membrane-bound organelle
Biological Process: peroxisome fission; endoplasmic reticulum organization and biogenesis; COPII coating of Golgi vesicle; protein transport; peroxisome organization and biogenesis
Research Articles on SEC16B
Similar Products
Product Notes
The SEC16B sec16b (Catalog #AAA150562) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LZTR2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LZTR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). LZTR2 antibody can be used for detection of LZTR2 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the SEC16B sec16b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LZTR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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