Immunohistochemistry (IHC)
(Immunohistochemistry Analysis: Representative lot data.Paraffin-embedded ovarian cancer tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:1,000 dilution ofMBS628739. Reactivity was detected (purple) using the IHC-Select Detection Kit. Staining pattern appears to be localized to peritumoral lymphatic vessels.)
Rabbit anti-Human LYVE-1 Polyclonal Antibody | anti-LYVE-1 antibody
LYVE-1 (Lymphatic Vessel Endothelial Hyaluronic Acid Receptor, LYVE1, CRSBP1, Extracellular Link Domain Containing 1, Hyaluronic Acid Receptor, HAR, Lymphatic Endothelium Specific Hyaluronan Receptor, Lymphatic Vessel Endothelial Hyaluronan Receptor 1, XL
Applications are based on unconjugated antibody.
Immunohistochemistry (IHC)
(Immunohistochemistry Analysis: Representative lot data.Paraffin-embedded ovarian cancer tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:1,000 dilution ofMBS628739. Reactivity was detected (purple) using the IHC-Select Detection Kit. Staining pattern appears to be localized to peritumoral lymphatic vessels.)
Immunohistochemistry (IHC)
(Immunohistochemistry Analysis: Representative lot data.Paraffin-embedded ovarian cancer tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:1,000 dilution ofMBS628739. Reactivity was detected (purple) using the IHC-Select Detection Kit. Staining pattern appears to be localized to peritumoral lymphatic vessels.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Uniprot Description
XLKD1: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: transmembrane receptor activity; hyaluronic acid binding
Biological Process: glycosaminoglycan catabolic process; transport; cell adhesion; signal transduction
Research Articles on LYVE-1
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Product Notes
The LYVE-1 lyve1 (Catalog #AAA6485726) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LYVE-1 (Lymphatic Vessel Endothelial Hyaluronic Acid Receptor, LYVE1, CRSBP1, Extracellular Link Domain Containing 1, Hyaluronic Acid Receptor, HAR, Lymphatic Endothelium Specific Hyaluronan Receptor, Lymphatic Vessel Endothelial Hyaluronan Receptor 1, XL reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LYVE-1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:1000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LYVE-1 lyve1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LYVE-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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