Western Blot (WB)
(Western Blot analysis of PLA2G15 expression in transfected 293T cell line using MBS643530. Lane 1: PLA2G15 transfected lysate (46.7kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human LYPLA3 Polyclonal Antibody | anti-PLA2G15 antibody
LYPLA3 (PLA2G15, Group XV Phospholipase A2, 1-O-acylceramide Synthase, ACS, LCAT-like Lysophospholipase, LLPL, Lysophospholipase 3, Lysosomal Phospholipase A2, LPLA2, UNQ341/PRO540)
Serum
Serum
Western Blot (WB)
(Western Blot analysis of PLA2G15 expression in transfected 293T cell line using MBS643530. Lane 1: PLA2G15 transfected lysate (46.7kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PLA2G15 expression in transfected 293T cell line using MBS643530. Lane 1: PLA2G15 transfected lysate (46.7kD). Lane 2: Non-transfected lysate.)
Immunoprecipitation (IP)
(Immunoprecipitation of PLA2G15 transfected lysate using using MBS643530 and Protein A Magnetic Bead, and immunoblotted with PLA2G15 purified mouse polyclonal antibody.)
Immunoprecipitation (IP)
(Immunoprecipitation of PLA2G15 transfected lysate using using MBS643530 and Protein A Magnetic Bead, and immunoblotted with PLA2G15 purified mouse polyclonal antibody.)
NCBI and Uniprot Product Information
NCBI Description
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008]
Uniprot Description
LYPLA3: Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid. May have weak lysophospholipase activity. Belongs to the AB hydrolase superfamily. Lipase family.
Protein type: Transferase; Secreted; Phospholipase; Secreted, signal peptide; Lipid Metabolism - glycerophospholipid; EC 2.3.1.-
Chromosomal Location of Human Ortholog: 16q22.1
Cellular Component: mitochondrion; lysosome
Molecular Function: calcium-independent phospholipase A2 activity; phospholipid binding; O-acyltransferase activity; lysophospholipase activity
Biological Process: fatty acid catabolic process; ceramide metabolic process; phosphatidylcholine metabolic process
Research Articles on PLA2G15
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Product Notes
The PLA2G15 pla2g15 (Catalog #AAA643530) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LYPLA3 (PLA2G15, Group XV Phospholipase A2, 1-O-acylceramide Synthase, ACS, LCAT-like Lysophospholipase, LLPL, Lysophospholipase 3, Lysosomal Phospholipase A2, LPLA2, UNQ341/PRO540) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LYPLA3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). Suitable for use in Western Blot and Immunoprecipitation. Researchers should empirically determine the suitability of the PLA2G15 pla2g15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGLHLRPYRV GLLPDGLLFL LLLLMLLADP ALPAGRHPPV VLVPGDLGNQ LEAKLDKPTV VHYLCSKKTE SYFTIWLNLE LLLPVIIDCW IDNIRLVYNK TSRATQFPDG VDVRVPGFGK TFSLEFLDPS KSSVGSYFHT MVESLVGWGY TRGEDVRGAP YDWRRAPNEN GPYFLALREM IEEMYQLYGG PVVLVAHSMG NMYTLYFLQR QPQAWKDKYI RAFVSLGAPW GGVAKTLRVL ASGDNNRIPV IGPLKIREQQ RSAVSTSWLL PYNYTWSPEK VFVQTPTINY TLRDYRKFFQ DIGFEDGWLM RQDTEGLVEA TMPPGVQLHC LYGTGVPTPD SFYYESFPDR DPKICFGDGD GTVNLKSALQ CQAWQSRQEH QVLLQELPGS EHIEMLANAT TLAYLKRVLL GP. It is sometimes possible for the material contained within the vial of "LYPLA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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