Western Blot (WB)
(Anti- Lymphotactin Picoband antibody, MBS178257, Western blottingAll lanes: Anti Lymphotactin (MBS178257) at 0.5ug/mlWB: HELA Whole Cell Lysate at 40ugPredicted bind size: 13KDObserved bind size: 13KD )
anti-Human Lymphotactin Polyclonal Antibody | anti-XCL1 antibody
Anti-Lymphotactin Antibody
Western Blot (WB)
(Anti- Lymphotactin Picoband antibody, MBS178257, Western blottingAll lanes: Anti Lymphotactin (MBS178257) at 0.5ug/mlWB: HELA Whole Cell Lysate at 40ugPredicted bind size: 13KDObserved bind size: 13KD )
Western Blot (WB)
(Anti- Lymphotactin Picoband antibody, MBS178257, Western blottingAll lanes: Anti Lymphotactin (MBS178257) at 0.5ug/mlWB: HELA Whole Cell Lysate at 40ugPredicted bind size: 13KDObserved bind size: 13KD )
Background: Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the XC chemokine family that is also known as lymphotactin. Muller et al. (1995) mapped the gene to chromosome 1q23 by FISH. The sequence of the deduced 114-amino acid protein is most homologous to the CC chemokines CCL8 and CCL3. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces the migration of cells expressing XCR1.
NCBI and Uniprot Product Information
NCBI Description
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014]
Uniprot Description
XCL1: Chemotactic activity for lymphocytes but not for monocytes or neutrophils. Belongs to the intercrine gamma family.
Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 1q23
Cellular Component: extracellular region; extracellular space; intracellular
Molecular Function: CCR chemokine receptor binding; chemokine activity; chemokine receptor binding; protein homodimerization activity
Biological Process: cell-cell signaling; G-protein coupled receptor protein signaling pathway; monocyte chemotaxis; negative regulation of interferon-gamma production; negative regulation of interleukin-2 production; negative regulation of T cell cytokine production; negative regulation of T-helper 1 type immune response; negative regulation of transcription factor activity; negative regulation of transcription, DNA-dependent; neutrophil chemotaxis; positive regulation of GTPase activity; positive regulation of inflammatory response; positive regulation of interleukin-10 production; positive regulation of leukocyte chemotaxis; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of T cell cytokine production; positive regulation of T cell mediated cytotoxicity; regulation of inflammatory response; release of sequestered calcium ion into cytosol; response to virus; signal transduction
Research Articles on XCL1
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Product Notes
The XCL1 xcl1 (Catalog #AAA178257) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Lymphotactin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lymphotactin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the XCL1 xcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lymphotactin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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