Western Blot (WB)
(Western blot analysis of LRRFIP1 expression in HeLa (A), LO2 (B) whole cell lysates.)
Rabbit anti-Human LRRFIP1 Polyclonal Antibody | anti-LRRFIP1 antibody
Anti-LRRFIP1 Antibody
Western Blot (WB)
(Western blot analysis of LRRFIP1 expression in HeLa (A), LO2 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of LRRFIP1 expression in HeLa (A), LO2 (B) whole cell lysates.)
NCBI and Uniprot Product Information
Uniprot Description
LRRFIP1: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: cytoskeleton; cytoplasm; plasma membrane; cytosol; nucleus
Molecular Function: protein binding; protein homodimerization activity; DNA binding; double-stranded RNA binding
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; positive regulation of interferon type I production; innate immune response; negative regulation of transcription, DNA-dependent
Research Articles on LRRFIP1
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Product Notes
The LRRFIP1 lrrfip1 (Catalog #AAA8307181) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LRRFIP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRFIP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the LRRFIP1 lrrfip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRFIP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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