Rabbit anti-Human LRRC8B Polyclonal Antibody | anti-LRRC8B antibody

LRRC8B, NT (LRRC8B, KIAA0231, Leucine-rich repeat-containing protein 8B, T-cell activation leucine repeat-rich protein)

Cat. Num. AAA645869

• Gene Names: LRRC8B; TALRRP; TA-LRRP
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: LRRC8B; Polyclonal Antibody; NT (LRRC8B; KIAA0231; Leucine-rich repeat-containing protein 8B; T-cell activation leucine repeat-rich protein); Anti -LRRC8B; anti-LRRC8B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-LRRC8B antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:10-50
• Immunogen: LRRC8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the N-terminal region of human LRRC8B.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LRRC8B Antibody (N-term ) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the LRRC8B antibody detected the LRRC8B protein (arrow).)

Immunohistochemistry (IHC)

(LRRC8B Antibody (N-term ) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LRRC8B Antibody (N-term ) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-LRRC8B antibody

The exact function of LRRC8B remains unknown.

Product Categories/Family for anti-LRRC8B antibody

Antibodies; Abs to Leucine-rich Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 71296878
• NCBI GeneID: 23507
• UniProt Accession #: Q6P9F7; Q6UY21; Q8N106; Q92627; D3DT28
• Molecular Weight: 92,390 Da
• NCBI Official Full Name: LRRC8B protein
• NCBI Official Synonym Full Names: leucine rich repeat containing 8 family, member B
• NCBI Official Symbol: LRRC8B
• NCBI Official Synonym Symbols: TALRRP; TA-LRRP
• NCBI Protein Information: leucine-rich repeat-containing protein 8B; T cell activation leucine repeat rich protein; T-cell activation leucine repeat-rich protein
• UniProt Protein Name: Leucine-rich repeat-containing protein 8B
• Protein Family: Volume-regulated anion channel
• UniProt Gene Name: LRRC8B
• UniProt Synonym Gene Names: KIAA0231; TA-LRRP
• UniProt Entry Name: LRC8B_HUMAN

Uniprot Description

Subcellular location: Membrane; Multi-pass membrane protein

Potential.

Sequence similarities: Contains 13 LRR (leucine-rich) repeats.

Sequence caution: The sequence BAA13220.2 differs from that shown. Reason: Erroneous initiation.