Western Blot (WB)
(Figure 1. Western blot analysis of LRRC32 using anti-LRRC32 antibody.)
Rabbit anti-Human LRRC32 Polyclonal Antibody | anti-LRRC32 antibody
Anti-LRRC32 Antibody
Gene Names
LRRC32; GARP; D11S833E
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Immunogen affinity purified.
Synonyms
LRRC32; Polyclonal Antibody; Anti-LRRC32 Antibody; Transforming growth factor beta activator LRRC32; Garpin; Glycoprotein A repetitions predominant; GARP; Leucine-rich repeat-containing protein 32; D11S833E; anti-LRRC32 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
662
Applicable Applications for anti-LRRC32 antibody
Western Blot (WB), Direct ELISA (EIA)
Application Notes
WB: 0.25-0.5ug/ml (Human)
Direct ELISA: 0.1-0.5ug/ml (Human)
Tested Species: In-house tested species with positive results.
Direct ELISA: 0.1-0.5ug/ml (Human)
Tested Species: In-house tested species with positive results.
Immunogen
E Coli-derived human LRRC32 recombinant protein (Position: H20-R544).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Figure 1. Western blot analysis of LRRC32 using anti-LRRC32 antibody.)
Western Blot (WB)
(Figure 1. Western blot analysis of LRRC32 using anti-LRRC32 antibody.)
Related Product Information for anti-LRRC32 antibody
Description: Rabbit IgG polyclonal antibody for LRRC32 detection. Tested with WB, Direct ELISA in Human.
Background: Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant), is an 80 kDa type I transmembrane glycoprotein. It is mapped to 11q13.5. This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.
Background: Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant), is an 80 kDa type I transmembrane glycoprotein. It is mapped to 11q13.5. This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.
References
1. Lienart, S., Merceron, R., Vanderaa, C., Lambert, F., Colau, D., Stockis, J., van der Woning, B., De Haard, H., Saunders, M., Coulie, P. G., Savvides, S. N., Lucas, S. Structural basis of latent TGF-beta-1 presentation and activation by GARP on human regulatory T cells. Science 362: 952-956, 2018.
2. Ollendorff, V., Noguchi, T., deLapeyriere, O., Birnbaum, D. The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth Diff. 5: 213-219, 1994.
3. Ollendorff, V., Szepetowski, P., Mattei, M.-G., Gaudray, P., Birnbaum, D. New gene in the homologous human 11q13-q14 and mouse 7F chromosomal regions. Mammalian Genome 2: 195-200, 1992.
2. Ollendorff, V., Noguchi, T., deLapeyriere, O., Birnbaum, D. The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth Diff. 5: 213-219, 1994.
3. Ollendorff, V., Szepetowski, P., Mattei, M.-G., Gaudray, P., Birnbaum, D. New gene in the homologous human 11q13-q14 and mouse 7F chromosomal regions. Mammalian Genome 2: 195-200, 1992.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Transforming growth factor beta activator LRRC32
NCBI Official Synonym Full Names
leucine rich repeat containing 32
NCBI Official Symbol
LRRC32
NCBI Official Synonym Symbols
GARP; D11S833E
NCBI Protein Information
transforming growth factor beta activator LRRC32
UniProt Protein Name
Leucine-rich repeat-containing protein 32
Protein Family
UniProt Gene Name
LRRC32
UniProt Synonym Gene Names
D11S833E; GARP; GARP
UniProt Entry Name
LRC32_HUMAN
NCBI Description
This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies. [provided by RefSeq, Jul 2008]
Uniprot Description
LRRC32:
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q13.5-q14
Cellular Component: integral to plasma membrane
Research Articles on LRRC32
Similar Products
Product Notes
The LRRC32 lrrc32 (Catalog #AAA1753161) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LRRC32 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRC32 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Direct ELISA (EIA). WB: 0.25-0.5ug/ml (Human) Direct ELISA: 0.1-0.5ug/ml (Human) Tested Species: In-house tested species with positive results. Researchers should empirically determine the suitability of the LRRC32 lrrc32 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRC32, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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