Rabbit LRFN3 Polyclonal Antibody | anti-LRFN3 antibody

LRFN3 Antibody

Cat. Num. AAA9402884

• Gene Names: LRFN3; SALM4; FIGLER1
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity chromatography purified via peptide column
• Synonyms: LRFN3; Polyclonal Antibody; LRFN3 Antibody; Leucine-rich repeat and fibronectin type III domain-containing protein 3; synaptic adhesion-like molecule 4; SALM4; FIGLER1; anti-LRFN3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: This antibody is predicted to not cross-react with other members of the LRFN family.
• Purity/Purification: Affinity chromatography purified via peptide column
• Form/Format: Supplied in PBS containing 0.02% sodium azide.
• Sequence Length: 628

• Applicable Applications for anti-LRFN3 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen Type: Peptide
• Immunogen Description: Raised against a 16 amino acid peptide near the center of human LRFN3.
• Target Name: LRFN3
• Preparation and Storage: Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of LRFN3 in K562 lysate with LRFN3 antibody at (A) 1 and (B) 2 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of LRFN3 in mouse brain tissue with LRFN3 antibody at 2.5 ug/mL.)

Related Product Information for anti-LRFN3 antibody

LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

Product Categories/Family for anti-LRFN3 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 13375646
• NCBI GeneID: 79414
• NCBI Accession #: NP_078785
• NCBI GenBank Nucleotide #: NM_024509.1
• Molecular Weight: 66,260 Da
• NCBI Official Full Name: leucine-rich repeat and fibronectin type-III domain-containing protein 3
• NCBI Official Synonym Full Names: leucine rich repeat and fibronectin type III domain containing 3
• NCBI Official Symbol: LRFN3
• NCBI Official Synonym Symbols: SALM4; FIGLER1
• NCBI Protein Information: leucine-rich repeat and fibronectin type-III domain-containing protein 3
• UniProt Protein Name: Leucine-rich repeat and fibronectin type-III domain-containing protein 3
• Protein Family: Leucine-rich repeat and fibronectin type-III domain-containing protein
• UniProt Gene Name: LRFN3
• UniProt Synonym Gene Names: SALM4
• UniProt Entry Name: LRFN3_HUMAN

Uniprot Description

LRFN3: Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons. Belongs to the LRFN family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: presynaptic membrane; postsynaptic membrane; axon; dendrite; integral to membrane; cell junction

Biological Process: cell adhesion