Western Blot (WB)
(Western blot analysis of LRFN1 in human brain lysate with LRFN1 antibody at (A) 1 and (B) 2 μg/mL.)
Rabbit LRFN1 Polyclonal Antibody | anti-LRFN1 antibody
LRFN1 Antibody
Gene Names
LRFN1; SALM2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
LRFN1 Antibody is affinity chromatography purified via peptide column.
Synonyms
LRFN1; Polyclonal Antibody; LRFN1 Antibody; SALM2; KIAA1484; Leucine-rich repeat and fibronectin type III domain-containing protein 1; Synaptic adhesion-like molecule 2; leucine rich repeat and fibronectin type III domain containing 1; anti-LRFN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody is predicted to not cross-react with other members of the LRFN family.
Purity/Purification
LRFN1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
771
Applicable Applications for anti-LRFN1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
LRFN1 antibody can be used for detection of LRFN1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
LRFN1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LRFN1.
Buffer
LRFN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
LRFN1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of LRFN1 in human brain lysate with LRFN1 antibody at (A) 1 and (B) 2 μg/mL.)
Western Blot (WB)
(Western blot analysis of LRFN1 in human brain lysate with LRFN1 antibody at (A) 1 and (B) 2 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of LRFN1 in mouse brain tissue with LRFN1 antibody at 2.5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of LRFN1 in mouse brain tissue with LRFN1 antibody at 2.5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of LRFN1 in mouse brain tissue with LRFN1 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of LRFN1 in mouse brain tissue with LRFN1 antibody at 20 μg/mL.)
Related Product Information for anti-LRFN1 antibody
LRFN1 Antibody: LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
82,318 Da
NCBI Official Full Name
Leucine-rich repeat and fibronectin type III domain-containing protein 1
NCBI Official Synonym Full Names
leucine rich repeat and fibronectin type III domain containing 1
NCBI Official Symbol
LRFN1
NCBI Official Synonym Symbols
SALM2
NCBI Protein Information
leucine-rich repeat and fibronectin type III domain-containing protein 1; synaptic adhesion-like molecule 2
UniProt Protein Name
Leucine-rich repeat and fibronectin type III domain-containing protein 1
UniProt Gene Name
LRFN1
UniProt Synonym Gene Names
KIAA1484; SALM2
UniProt Entry Name
LRFN1_HUMAN
Uniprot Description
LRFN1: Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1. Belongs to the LRFN family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: postsynaptic membrane; postsynaptic density; integral to membrane; cell junction
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Product Notes
The LRFN1 lrfn1 (Catalog #AAA150597) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRFN1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LRFN1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). LRFN1 antibody can be used for detection of LRFN1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the LRFN1 lrfn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRFN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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