Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A549 cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Rabbit anti-Human LLGL1 Polyclonal Antibody | anti-LLGL1 antibody
LLGL1 Antibody
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A549 cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A549 cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Uniprot Description
LLGL1: Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Belongs to the WD repeat L(2)GL family.
Protein type: Motility/polarity/chemotaxis; Cell adhesion; Cytoskeletal
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: Golgi membrane; cortical actin cytoskeleton; cytoskeleton; early endosome membrane; axon; cytoplasm; Golgi cis cisterna; trans-Golgi network membrane
Molecular Function: protein binding; structural molecule activity; protein kinase binding
Biological Process: Golgi to plasma membrane transport; exocytosis; axonogenesis; protein complex assembly; cortical actin cytoskeleton organization and biogenesis; maintenance of apical/basal cell polarity
Research Articles on LLGL1
Similar Products
Product Notes
The LLGL1 llgl1 (Catalog #AAA9404139) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LLGL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LLGL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:2000. Researchers should empirically determine the suitability of the LLGL1 llgl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LLGL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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