Testing Data
(Detection limit for recombinant GST tagged TIE1 is ~1ng/ml as a capture antibody.)
Mouse anti-Human TIE1 Monoclonal Antibody | anti-TIE1 antibody
TIE1 (Tyrosine-protein Kinase Receptor Tie-1, TIE, JTK14) (AP)
Gene Names
TIE1; TIE; JTK14
Reactivity
Human
Applications
ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
TIE1; Monoclonal Antibody; TIE1 (Tyrosine-protein Kinase Receptor Tie-1; TIE; JTK14) (AP); EC=2.7.10.1; anti-TIE1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3F4
Specificity
Recognizes human TIE1.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-TIE1 antibody
ELISA (EIA)
Application Notes
ELISA: 1ng/ml
Applications are based on unconjugated antibody.
Applications are based on unconjugated antibody.
Immunogen
Partial recombinant corresponding to aa422-521 from human TIE1 (NP_005415) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
GFWECRVSTSGGQDSRRFKVNVKVPPVPLAAPRLLTKQSRQLVVSPLVSFSGDGPISTVRLHYRPQDSTMDWSTIVVDPSENVTLMNLRPKTGYSVRVQ
Conjugate
AP
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Testing Data
(Detection limit for recombinant GST tagged TIE1 is ~1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged TIE1 is ~1ng/ml as a capture antibody.)
Product Categories/Family for anti-TIE1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,138 Da
NCBI Official Full Name
tyrosine-protein kinase receptor Tie-1 isoform 1
NCBI Official Synonym Full Names
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
NCBI Official Symbol
TIE1
NCBI Official Synonym Symbols
TIE; JTK14
NCBI Protein Information
tyrosine-protein kinase receptor Tie-1; tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1
UniProt Protein Name
Tyrosine-protein kinase receptor Tie-1
Protein Family
UniProt Gene Name
TIE1
UniProt Synonym Gene Names
TIE
UniProt Entry Name
TIE1_HUMAN
Uniprot Description
TIE1: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
Protein type: Kinase, protein; Protein kinase, TK; Membrane protein, integral; EC 2.7.10.1; Protein kinase, tyrosine (receptor); TK group; Tie family
Chromosomal Location of Human Ortholog: 1p34-p33
Cellular Component: integral to plasma membrane
Molecular Function: protein binding; transmembrane receptor protein tyrosine kinase activity; ATP binding
Biological Process: negative regulation of angiogenesis; peptidyl-tyrosine phosphorylation; response to retinoic acid; in utero embryonic development; mesoderm development; angiogenesis; signal transduction; vasculogenesis; negative regulation of cell migration; plasma membrane fusion
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Product Notes
The TIE1 tie1 (Catalog #AAA6134201) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TIE1 (Tyrosine-protein Kinase Receptor Tie-1, TIE, JTK14) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TIE1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1ng/ml Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TIE1 tie1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIE1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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