Western Blot (WB)
(Sample Data: Western blot analysis of LKB1 in PC-3 cell lysate with LKB1 antibody at 1 ug/ml in the (A) absence or (B) presence of blocking peptide.)
Rabbit anti-Human, Mouse LKB1 (STK11) Polyclonal Antibody | anti-LKB1 antibody
Anti-LKB1 (STK11)
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Affinity chromatography
Synonyms
LKB1 (STK11); Polyclonal Antibody; Anti-LKB1 (STK11); anti-LKB1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit, IgG
Specificity
Recognizes the LKB1 (STK11) protein
Purity/Purification
Affinity chromatography
Form/Format
PBS + 0.02% sodium azide
Applicable Applications for anti-LKB1 antibody
Western Blot (WB), ELISA
Immunogen
LKB1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human LKB1
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
1 year at -20 degree C from date of shipment
1 year at -20 degree C from date of shipment
Western Blot (WB)
(Sample Data: Western blot analysis of LKB1 in PC-3 cell lysate with LKB1 antibody at 1 ug/ml in the (A) absence or (B) presence of blocking peptide.)
Western Blot (WB)
(Sample Data: Western blot analysis of LKB1 in PC-3 cell lysate with LKB1 antibody at 1 ug/ml in the (A) absence or (B) presence of blocking peptide.)
Related Product Information for anti-LKB1 antibody
LKB1(STK11) is a member of the serine/threonine kinase family which regulates cell polarity and functions as a tumor suppressor. STK11 is a critical barrier to pulmonary tumorigenesis which controlling initiation, differentiation, and metastasis. STK11 plays a central role in restricting HSC entry into cell cycle and in broadly maintaining energy homeostasis in hematopoietic cells through a novel metabolic checkpoint (1). STK11 serves as an essential regulator of HSCs and hematopoiesis, and more generally, points to the critical importance of coupling energy metabolism and stem cell homeostasis (2).
Product Categories/Family for anti-LKB1 antibody
References
1. Gurumurthy, S. et.al: The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468: 659-663, 2010. Note: Erratum: Nature 476: 114 only, 2011.
2. Gan, B.et.al: Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468: 701-704, 2010.
2. Gan, B.et.al: Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468: 701-704, 2010.
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Product Notes
The LKB1 (Catalog #AAA516051) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LKB1 (STK11) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LKB1 (STK11) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA. Researchers should empirically determine the suitability of the LKB1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LKB1 (STK11), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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