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Rabbit Livin Polyclonal Antibody | anti-LIVIN antibody

Livin Antibody

Gene Names
BIRC7; KIAP; LIVIN; MLIAP; RNF50; ML-IAP
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Chromatography
Synonyms
Livin; Polyclonal Antibody; Livin Antibody; Rabbit Polyclonal Livin Antibody; Polyclonal Livin antibody; anti-Livin antibody; MLIAP antibody; RNF50 antibody; BIRC7 antibody; ML-IAP antibody; Livin antibody; KIAP antibody; anti-LIVIN antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer, pH 7.2, containing 30% Glycerol, 0.5% BSA, 0.01% Thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
298
Applicable Applications for anti-LIVIN antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
WB: 2-6 ug/ml
Immunogen
Livin antibody was raised in Rabbit using synthetic peptide surrounding amino acid near the C-terminus of the long form of human Livin as the immunogen.
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-LIVIN antibody
Livin is a novel member in the IAP protein family. Livin contains a single baculoviral IAP repeat domain and a RING finger domain and has two isoforms termed Livin-alpha and Livin-beta. Transfection of Livin protected cells from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6. Livin directly reacts with several caspases including Caspase-3, -7, and -9, and it inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c and ATP.
Product Categories/Family for anti-LIVIN antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
LIVIN
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 7
NCBI Official Symbol
BIRC7
NCBI Official Synonym Symbols
KIAP; LIVIN; MLIAP; RNF50; ML-IAP
NCBI Protein Information
baculoviral IAP repeat-containing protein 7

NCBI Description

This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]

Research Articles on LIVIN

Similar Products

Product Notes

The LIVIN (Catalog #AAA5311262) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Livin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). WB: 2-6 ug/ml. Researchers should empirically determine the suitability of the LIVIN for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Livin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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