Western Blot (WB)
(Western blot analysis of LCN2 in20ug mouse aorta tissue lysateusing anti-mouse LCN2 followedby goat anti-rabbit antibody)
Rabbit anti-Mouse Lipocalin-2 (NGAL) Polyclonal Antibody | anti-LCN2 antibody
Lipocalin-2 (NGAL): Mouse, Rabbit polyclonal Antibody
Gene Names
LCN2; p25; 24p3; MSFI; NGAL
Reactivity
Mouse
Applications
Western Blot, ELISA, Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Purity
Rabbit specific IgG was purified by mouse LCN2 affinity chromatography
Synonyms
Lipocalin-2 (NGAL); Polyclonal Antibody; Lipocalin-2 (NGAL): Mouse; Rabbit polyclonal Antibody; Lipocalin 2 (LCN2); Polyclonal Antibody against Mouse Lipocalin 2; anti-LCN2 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
The antibody detects mouse LCN2.
Purity/Purification
Rabbit specific IgG was purified by mouse LCN2 affinity chromatography
Form/Format
Solution in PBS
Sequence Length
198
Applicable Applications for anti-LCN2 antibody
Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP), Immunostaining
Application Notes
WB: This antibody can be used as primaryantibody to detect mouse LCN2.
ELISA: This antibody can be used in ELISA with the appropriate secondary reagents to detect mouse LCN2.
ELISA: This antibody can be used in ELISA with the appropriate secondary reagents to detect mouse LCN2.
Immunogen
Recombinant full-length mouse LCN2 expressed in E Coli
Preparation and Storage
Store at -20 degree C. For long-term storage, aliquot and freeze at -70 degree C. Avoid repeated freeze/defrost cycles.
Western Blot (WB)
(Western blot analysis of LCN2 in20ug mouse aorta tissue lysateusing anti-mouse LCN2 followedby goat anti-rabbit antibody)
Western Blot (WB)
(Western blot analysis of LCN2 in20ug mouse aorta tissue lysateusing anti-mouse LCN2 followedby goat anti-rabbit antibody)
Related Product Information for anti-LCN2 antibody
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), 24p3, or neutrophil lipocalin (NL), is a 25-kDa secretory glycoprotein which is expressed in liver, lung,kidney, adipocytes, activated neutrophils, and macrophages. LCN2 appears to be upregulated inthe case of information and infection conditions. LCN2 has been implicated in a variety of cellular processes including the innate immune response, infection, differentiation, tumorigenesis and cell survival. It appears to be up- regulated in various inflammation and infection conditions. Several reports suggest that LCN2 may represent a sensitive biomarker for various renal and lung injuries and is associated with several types of cancers, including breast cancer, ovarian, colorectal and pancreatic cancers. Furthermore, serum levels of LCN2 are correlated with obesity, insulin resistance, hyperglycemia, coronary heart disease and fatty liver disease in humans. LCN2 is also high expressed underhigh fat diet and obese background especially in adipose tissue and is closely associated withobesity, insulin resistance, and hyperglycemia in humans.
References
1. A emerging clinical and experimental evidence for the role of lipocalin-2 in metabolic syndrome. Jang Y, Lee JH, Wang Y, Sweeney G. Clin Exp Pharmacol Physiol. 2012 Feb;39(2):194-9
2. The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer. Chakraborty S, Kaur S, Guha S, Batra SK. Biochim Biophys Acta. 2012 Aug;1826(1):129-69.
2. The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer. Chakraborty S, Kaur S, Guha S, Batra SK. Biochim Biophys Acta. 2012 Aug;1826(1):129-69.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Lipocalin 2
NCBI Official Synonym Full Names
lipocalin 2
NCBI Official Symbol
LCN2
NCBI Official Synonym Symbols
p25; 24p3; MSFI; NGAL
NCBI Protein Information
neutrophil gelatinase-associated lipocalin
Protein Family
NCBI Description
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
Research Articles on LCN2
Similar Products
Product Notes
The LCN2 (Catalog #AAA398032) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Lipocalin-2 (NGAL): Mouse, Rabbit polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Lipocalin-2 (NGAL) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP), Immunostaining. WB: This antibody can be used as primaryantibody to detect mouse LCN2. ELISA: This antibody can be used in ELISA with the appropriate secondary reagents to detect mouse LCN2. Researchers should empirically determine the suitability of the LCN2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lipocalin-2 (NGAL), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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