Rabbit LIAR Polyclonal Antibody | anti-LIAR antibody

LIAR Antibody

Cat. Num. AAA9403966

• Gene Names: ANKRD54; LIAR
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity chromatography purified via peptide column
• Synonyms: LIAR; Polyclonal Antibody; LIAR Antibody; Lyn-interacting ankyrin repeat protein; ankyrin repeat domain 54; ANKRD54; anti-LIAR antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Affinity chromatography purified via peptide column
• Form/Format: Supplied in PBS containing 0.02% sodium azide.
• Sequence Length: 300

• Applicable Applications for anti-LIAR antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen Type: Peptide
• Immunogen Description: Raised against a 16 amino acid peptide near the carboxy terminus of human LIAR.
• Target Name: LIAR
• Preparation and Storage: Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of LIAR in mouse kidney tissue lysate with LIAR antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)

Immunohistochemistry (IHC)

(Immunohistochemistry of LIAR in mouse kidney tissue with LIAR antibody at 2.5 ug/mL.)

Related Product Information for anti-LIAR antibody

Ankyrin (ANK) repeats mediate protein-protein interactions in diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20. ANK repeats may occur in combinations with other types of domains. The structural repeat unit contains two anti-parallel helices and a beta-hairpin, with repeats stacked in a superhelical arrangement. LIAR, also known as ANKRD54, is a recently identified ANK repeat-containing protein that is predominantly expressed in tissues rich in cilliated cells, such as olfactory sensory neurons and is predicted to be important to cilia. At least three isoforms of LIAR are known to exist.

Product Categories/Family for anti-LIAR antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 20270347
• NCBI GeneID: 129138
• NCBI Accession #: NP_620152
• NCBI GenBank Nucleotide #: NM_138797.2
• Molecular Weight: 18,254 Da
• NCBI Official Full Name: ankyrin repeat domain-containing protein 54
• NCBI Official Synonym Full Names: ankyrin repeat domain 54
• NCBI Official Symbol: ANKRD54
• NCBI Official Synonym Symbols: LIAR
• NCBI Protein Information: ankyrin repeat domain-containing protein 54
• UniProt Protein Name: Ankyrin repeat domain-containing protein 54
• Protein Family: Transcriptional regulatory protein
• UniProt Gene Name: ANKRD54
• UniProt Synonym Gene Names: LIAR
• UniProt Entry Name: ANR54_HUMAN

Uniprot Description

ANKRD54: Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm; midbody; nucleus

Molecular Function: protein complex binding; protein kinase regulator activity

Biological Process: positive regulation of erythrocyte differentiation; nucleocytoplasmic transport; regulation of protein kinase activity