Immunohistochemistry (IHC)
(Immunochemical staining of human LDOC1 in human ovarian cancer with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Rabbit anti-Human LDOC1 Polyclonal Antibody | anti-LDOC1 antibody
Anti-LDOC1 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
LDOC1; Polyclonal Antibody; Anti-LDOC1 Antibody; Rabbit Polyclonal; LDOC1 Antibody; Rabbit PAb; Antigen Affinity Purified; leucine zipper; down-regulated in cancer 1; Anti-42070 Antibody; Anti-BCUR1 Antibody; Anti-Mart7 Antibody; anti-LDOC1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human LDOC1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-LDOC1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:500-1:2000
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human LDOC1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human LDOC1, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human LDOC1 in human ovarian cancer with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human LDOC1 in human ovarian cancer with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-LDOC1 antibody
LDOC1 (LDOC1 Regulator Of NFKB Signaling) is a Protein Coding gene. The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. LDOC1 was first identified as a gene encoding a leucine zipper protein whose expression was decreased in a series of pancreatic and gastric cancer cell lines. LDOC1 gene is a known regulator of the nuclear factor-mediated pathway to apoptosis through inhibition of nuclear factor kappa B (NF-kappaB). Upregulation of LDOC1 in HIBEC increases the expression of NF-kappaB, which may promote the activation of IL-2 and TNF-alpha secretion and inhibit cell apoptosis. The silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.
NCBI and Uniprot Product Information
Uniprot Description
LDOC1: May have an important role in the development and/or progression of some cancers. Belongs to the LDOC1 family.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: Xq27
Cellular Component: nucleolus; nucleus
Molecular Function: protein binding
Biological Process: negative regulation of cell proliferation
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Product Notes
The LDOC1 ldoc1 (Catalog #AAA8102258) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LDOC1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LDOC1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the LDOC1 ldoc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LDOC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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