Rabbit anti-Human, Rat LCMT1 Polyclonal Antibody | anti-LCMT1 antibody
LCMT1 Antibody
WB: 1:200-1:1000
IHC: 1:25-1:100
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125886(LCMT1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MBS7125886(LCMT1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))
SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: 231 cells, Primary antibody: MBS7125886(LCMT1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
NCBI and Uniprot Product Information
NCBI Description
LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008]
Uniprot Description
LCMT1: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Belongs to the methyltransferase superfamily. LCMT family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - histidine; EC 2.1.1.233; Lipid Metabolism - androgen and estrogen; Methyltransferase; Other Amino Acids Metabolism - selenoamino acid
Chromosomal Location of Human Ortholog: 16p12.1
Cellular Component: cytosol
Molecular Function: protein binding; C-terminal protein carboxyl methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity
Biological Process: regulation of apoptosis; protein amino acid methylation; C-terminal protein amino acid methylation; protein modification process; negative regulation of protein complex assembly
Research Articles on LCMT1
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Product Notes
The LCMT1 lcmt1 (Catalog #AAA7125886) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LCMT1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LCMT1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:2000 WB: 1:200-1:1000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the LCMT1 lcmt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LCMT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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