Immunohistochemistry (IHC)
(Immunochemical staining LAPTM4A in human bladder with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Rabbit LAPTM4A Polyclonal Antibody | anti-LAPTM4A antibody
Anti-LAPTM4A Antibody, Rabbit Polyclonal
Gene Names
LAPTM4A; MBNT; Mtrp; LAPTM4; HUMORF13
Reactivity
Human, RatPredicted to React with: Mouse, Cynomolgus (Species predicted to react based on 100% sequence homology)
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
LAPTM4A; Polyclonal Antibody; Anti-LAPTM4A Antibody; Rabbit Polyclonal; LAPTM4A Antibody; Rabbit PAb; Antigen Affinity Purified; lysosomal protein transmembrane 4 alpha; Anti-HUMORF13 Antibody; Anti-LAPTM4 Antibody; Anti-MBNT Antibody; Anti-Mtrp Antibody; anti-LAPTM4A antibody
Host
Rabbit
Reactivity
Human, Rat
Predicted to React with: Mouse, Cynomolgus (Species predicted to react based on 100% sequence homology)
Predicted to React with: Mouse, Cynomolgus (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human LAPTM4A
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-LAPTM4A antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:200-1:1000
Immunogen
A synthetic peptide corresponding to the center region of the Human LAPTM4A
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human LAPTM4A, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining LAPTM4A in human bladder with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining LAPTM4A in human bladder with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining LAPTM4A in rat bladder with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining LAPTM4A in rat bladder with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-LAPTM4A antibody
LAPTM4A (Lysosomal Protein Transmembrane 4 Alpha) is a Protein Coding gene. This gene encodes a protein that has four predicted transmembrane domains. It belongs to the LAPTM4/LAPTM5 transporter family. Studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes. Screening within a mating-based split-ubiquitin-yeast-two-hybrid system (mBSUS) revealed the LAPTM4A as a potential interacting protein. Interaction of LAPTM4A and hOCT2 was confirmed by pulldown assays, FRET microscopy analysis, and immunofluorescence microscopy.LAPTM4A has been identified as an interaction partner of hOCT2. LAPTM4A regulates the function of hOCT2 by influencing its trafficking to/from the cell membrane and processing it via the intracellular sorting machinery.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,801 Da
NCBI Official Full Name
lysosomal-associated transmembrane protein 4A
NCBI Official Synonym Full Names
lysosomal protein transmembrane 4 alpha
NCBI Official Symbol
LAPTM4A
NCBI Official Synonym Symbols
MBNT; Mtrp; LAPTM4; HUMORF13
NCBI Protein Information
lysosomal-associated transmembrane protein 4A
UniProt Protein Name
Lysosomal-associated transmembrane protein 4A
Protein Family
UniProt Gene Name
LAPTM4A
UniProt Synonym Gene Names
KIAA0108; LAPTM4; MBNT; MTRP
NCBI Description
This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes. [provided by RefSeq, Jul 2008]
Uniprot Description
May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.
Research Articles on LAPTM4A
1. hOCT2 interacts with LAPTM4A in lysosomes and late endosomes and regulates endocytotic recruitment.
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Product Notes
The LAPTM4A laptm4a (Catalog #AAA8102743) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LAPTM4A Antibody, Rabbit Polyclonal reacts with Human, Rat Predicted to React with: Mouse, Cynomolgus (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's LAPTM4A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the LAPTM4A laptm4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAPTM4A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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