Immunofluorescence (IF)
(Immunofluorescence analysis of COS-7 cells, using LAMA1 antibody. )
Rabbit anti-Human LAMA1 Polyclonal Antibody | anti-LAMA1 antibody
LAMA1 Antibody
Immunofluorescence (IF)
(Immunofluorescence analysis of COS-7 cells, using LAMA1 antibody. )
Immunofluorescence (IF)
(Immunofluorescence analysis of COS-7 cells, using LAMA1 antibody. )
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]
Uniprot Description
LAMA1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Protein type: Secreted; Extracellular matrix; Secreted, signal peptide; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 18p11.3
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; laminin-3 complex; laminin-1 complex; extracellular region; basement membrane; intercellular junction
Molecular Function: protein binding; extracellular matrix structural constituent; glycosphingolipid binding; receptor binding
Biological Process: regulation of cell adhesion; axon guidance; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; regulation of embryonic development; morphogenesis of an epithelial sheet; establishment of epithelial cell polarity; cell adhesion; regulation of cell migration
Disease: Poretti-boltshauser Syndrome
Research Articles on LAMA1
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Product Notes
The LAMA1 lama1 (Catalog #AAA7131080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LAMA1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LAMA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF). IF: 1:100-1:500. Researchers should empirically determine the suitability of the LAMA1 lama1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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