Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse L1-Cell Adhesion Molecule (L1CAM) Polyclonal Antibody | anti-L1CAM antibody
Polyclonal Antibody to L1-Cell Adhesion Molecule (L1CAM)
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF-SGLRPYSSY HVEVQAFNGR GLGPASEWTF STPEGVPGHP EALHLECQSD TSLLLHWQPP LSHNGVLTGY LLSYHPVEGE SKEQLFFNLS DPELRTHNLT NLNPDLQYRF QLQATTQQGG PGEAIVREGG TMALFGKPDF GNISATAGEN YSVVSWVPRK GQCNFRFHIL FKALPEGKVS PDHQPQPQYV SYNQSSYTQW NLQPDTKYEI HLIKEKVLLH HLDVKTNGTG PVRVSTTGSF ASEGWFIAFV SA
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
NCBI and Uniprot Product Information
Uniprot Description
NCAM-L1: cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons. Two splice-variant isoforms have been described.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: X A7.3|X 37.43 cM
Cellular Component: axon; axonal growth cone; cell projection; cell soma; cell surface; dendrite; dendritic growth cone; endosome; external side of plasma membrane; extracellular matrix; focal adhesion; integral component of membrane; membrane; membrane raft; plasma membrane; presynaptic membrane; terminal bouton
Molecular Function: identical protein binding; integrin binding; PDZ domain binding; protein binding; protein domain specific binding; protein self-association; sialic acid binding
Biological Process: axon guidance; axonal fasciculation; cell adhesion; cell differentiation; cell migration; cell surface receptor signaling pathway; cell-cell adhesion mediated by integrin; cell-matrix adhesion; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion; homotypic cell-cell adhesion; leukocyte adhesion; multicellular organism development; nervous system development; neuron projection development; positive regulation of axon extension; positive regulation of calcium-mediated signaling; positive regulation of cell-cell adhesion; positive regulation of cell-substrate adhesion; regulation of ERK1 and ERK2 cascade; synapse organization
Research Articles on L1CAM
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Product Notes
The L1CAM l1cam (Catalog #AAA2003221) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to L1-Cell Adhesion Molecule (L1CAM) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's L1-Cell Adhesion Molecule (L1CAM) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the L1CAM l1cam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF -SGLRPYSSY HVEVQAFNGR GLGPASEWTF STPEGVPGHP EALHLECQSD TSLLLHWQPP LSHNGVLTGY LLSYHPVEGE SKEQLFFNLS DPELRTHNLT NLNPDLQYRF QLQATTQQGG PGEAIVREGG TMALFGKPDF GNISATAGEN YSVVSWVPRK GQCNFRFHIL FKALPEGKVS PDHQPQPQYV SYNQSSYTQW NLQPDTKYEI HLIKEKVLLH HLDVKTNGTG PVRVSTTGSF ASEGWFIAFV SA. It is sometimes possible for the material contained within the vial of "L1-Cell Adhesion Molecule (L1CAM), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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