L-type Ca++ CP gamma 5 Polyclonal Antibody | anti-CACNG5 antibody

L-type Ca++ CP gamma 5 Polyclonal Antibody

Cat. Num. AAA8519585

• Synonyms: L-type Ca++ CP gamma 5; Polyclonal Antibody; L-type Ca++ CP gamma 5 Polyclonal Antibody; anti-CACNG5 antibody

• Clonality: Polyclonal
• Sequence Length: 275

NCBI and Uniprot Product Information

• NCBI GI #: 22027551
• NCBI GeneID: 27091
• NCBI Accession #: NP_665810.1
• NCBI GenBank Nucleotide #: NM_145811.2
• UniProt Accession #: Q9UF02; Q547R3; Q8WXS7; Q9UHM3; A8K2A6
• Molecular Weight: 30,903 Da
• NCBI Official Full Name: voltage-dependent calcium channel gamma-5 subunit
• NCBI Official Synonym Full Names: calcium voltage-gated channel auxiliary subunit gamma 5
• NCBI Official Symbol: CACNG5
• NCBI Protein Information: voltage-dependent calcium channel gamma-5 subunit
• UniProt Protein Name: Voltage-dependent calcium channel gamma-5 subunit
• Protein Family: Voltage-dependent calcium channel
• UniProt Gene Name: CACNG5
• UniProt Synonym Gene Names: TARP gamma-5

NCBI Description

The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010]

Uniprot Description

Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state ().