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Western Blot (WB) (Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue with Cav gamma5 Rabbit pAb EA196 diluted at 1:2,000. )

Rabbit Cav gamma5 Polyclonal Antibody | anti-Cav antibody

Cav gamma5 Rabbit pAb

Reactivity
Human, Rat, Mouse
Synonyms
Cav gamma5; Polyclonal Antibody; Cav gamma5 Rabbit pAb; acng5 antibody; TARP gamma-5 antibody; Transmembrane AMPAR regulatory protein gamma-5 antibody; anti-Cav antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Form/Format
PBS with 0.02% sodium azide and 50% glycerol pH7.4.
Concentration
1mg/ml (varies by lot)
Species
Human
Immunogen
Synthetic Peptide
Preparation and Storage
Store at -20 degree C. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue with Cav gamma5 Rabbit pAb EA196 diluted at 1:2,000. )

Western Blot (WB) (Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue with Cav gamma5 Rabbit pAb EA196 diluted at 1:2,000. )

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded  Rat Brain Tissue using Cav gamma5(EA196)Rabbit pAb diluted at 1:200.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded  Rat Brain Tissue using Cav gamma5(EA196)Rabbit pAb diluted at 1:200.)
Related Product Information for anti-Cav antibody
The gamma subunit is an integral membrane protein. The gamma family consists of at least 8 members, which share a number of common structural features. CaVgamma subunits inhibit CaV channel activity and modulate its activation and inactivation kinetics.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,903 Da
NCBI Official Synonym Full Names
calcium channel, voltage-dependent, gamma subunit 5
NCBI Official Symbol
CACNG5
NCBI Protein Information
voltage-dependent calcium channel gamma-5 subunit
UniProt Protein Name
Voltage-dependent calcium channel gamma-5 subunit
Protein Family
UniProt Gene Name
CACNG5
UniProt Synonym Gene Names
TARP gamma-5
UniProt Entry Name
CCG5_HUMAN

NCBI Description

The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010]

Uniprot Description

CACNG5: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, calcium

Chromosomal Location of Human Ortholog: 17q24

Cellular Component: postsynaptic membrane; postsynaptic density; cell junction

Molecular Function: voltage-gated calcium channel activity; ion transmembrane transporter activity

Biological Process: transport

Research Articles on Cav

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Product Notes

The Cav cacng5 (Catalog #AAA8808320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cav gamma5 Rabbit pAb reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Cav gamma5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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