Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blot analysis of Kv10.2 expression in HepG2 (A), mouse brain (B), rat brain (C) whole cell lysates.)

Kv10.2 Polyclonal Antibody | anti-KCNH5 antibody

Anti-Kv10.2 Antibody

Gene Names
KCNH5; EAG2; hEAG2; H-EAG2; Kv10.2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was purified by affinity chromatography.
Synonyms
Kv10.2; Polyclonal Antibody; Anti-Kv10.2 Antibody; EAG2; Potassium voltage-gated channel subfamily H member 5; Ether-a-go-go potassium channel 2; hEAG2; Voltage-gated potassium channel subunit Kv10.2; anti-KCNH5 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Kv10.2 protein.
Purity/Purification
The antibody was purified by affinity chromatography.
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Sequence Length
988
Applicable Applications for anti-KCNH5 antibody
Western Blot (WB), Immunohistochemistry (IH)
Application Notes
Western Blot: (1/1000 - 1/2000); Immunohistochemistry: (1/100 - 1/200)
Source
Rabbit
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence of human Kv10.2. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Kv10.2 expression in HepG2 (A), mouse brain (B), rat brain (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of Kv10.2 expression in HepG2 (A), mouse brain (B), rat brain (C) whole cell lysates.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of Kv10.2 staining in rat brain,mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of Kv10.2 staining in rat brain,mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Related Product Information for anti-KCNH5 antibody
Rabbit polyclonal to Kv10.2

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Potassium voltage-gated channel subfamily H member 5
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily H member 5
NCBI Official Symbol
KCNH5
NCBI Official Synonym Symbols
EAG2; hEAG2; H-EAG2; Kv10.2
NCBI Protein Information
potassium voltage-gated channel subfamily H member 5
UniProt Protein Name
Potassium voltage-gated channel subfamily H member 5
UniProt Gene Name
KCNH5
UniProt Synonym Gene Names
EAG2; hEAG2
UniProt Entry Name
KCNH5_HUMAN

NCBI Description

This gene encodes a member of voltage-gated potassium channels. Members of this family have diverse functions, including regulating neurotransmitter and hormone release, cardiac function, and cell volume. This protein is an outward-rectifying, noninactivating channel. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

Kv10.2: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly. Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.2/KCNH5 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, potassium; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q23.2

Cellular Component: cell surface; integral to membrane; intracellular; plasma membrane

Molecular Function: calmodulin binding; protein heterodimerization activity; two-component sensor activity; voltage-gated potassium channel activity

Biological Process: regulation of G2/M transition of mitotic cell cycle; regulation of membrane potential; synaptic transmission; two-component signal transduction system (phosphorelay)

Research Articles on KCNH5

Similar Products

Product Notes

The KCNH5 kcnh5 (Catalog #AAA8241822) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kv10.2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Kv10.2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IH). Western Blot: (1/1000 - 1/2000); Immunohistochemistry: (1/100 - 1/200). Researchers should empirically determine the suitability of the KCNH5 kcnh5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kv10.2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.