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Western Blot (WB) (Western blot analysis of p53 expression in mouse brain (A), rat brain (B) whole cell lysates.)

Rabbit anti-Mouse, Rat Kv8.2 Polyclonal Antibody | anti-KCNV2 antibody

Anti-Kv8.2 Antibody

Gene Names
Kcnv2; KV11.1
Reactivity
Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was purified by affinity chromatography.
Synonyms
Kv8.2; Polyclonal Antibody; Anti-Kv8.2 Antibody; Potassium voltage-gated channel subfamily V member 2; Voltage-gated potassium channel subunit Kv8.2; anti-KCNV2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Kv8.2 protein.
Purity/Purification
The antibody was purified by affinity chromatography.
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Sequence Length
562
Applicable Applications for anti-KCNV2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: (1/1000 - 1/2000); Immunohistochemistry: (1/100 - 1/200)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence of mouse Kv8.2. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of p53 expression in mouse brain (A), rat brain (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of p53 expression in mouse brain (A), rat brain (B) whole cell lysates.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of p53 staining in mouse colon formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of p53 staining in mouse colon formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Related Product Information for anti-KCNV2 antibody
Rabbit polyclonal to Kv8.2

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
64,461 Da
NCBI Official Full Name
Potassium voltage-gated channel subfamily V member 2
NCBI Official Synonym Full Names
potassium channel, subfamily V, member 2
NCBI Official Symbol
Kcnv2
NCBI Official Synonym Symbols
KV11.1
NCBI Protein Information
potassium voltage-gated channel subfamily V member 2
UniProt Protein Name
Potassium voltage-gated channel subfamily V member 2
UniProt Gene Name
Kcnv2
UniProt Entry Name
KCNV2_MOUSE

Uniprot Description

Kv8.2: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. Defects in KCNV2 are the cause of cone dystrophy retinal type 3B (RCD3B); also called cone dystrophy with night blindness and supernormal rod responses KCNV2-related. RCD3B is a rare form of cone dystrophy associated with supernormal rod responses. The disorder is characterized by reduced visual acuity, photoaversion, night blindness, and abnormal color vision. At an early age, the retina shows subtle depigmentation at the macula and, later, more obvious areas of atrophy. Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.2/KCNV2 sub-subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: integral to membrane; membrane; plasma membrane; voltage-gated potassium channel complex

Molecular Function: delayed rectifier potassium channel activity; ion channel activity; potassium channel activity; voltage-gated ion channel activity; voltage-gated potassium channel activity

Biological Process: ion transport; potassium ion transport; protein homooligomerization; transmembrane transport; transport

Research Articles on KCNV2

Similar Products

Product Notes

The KCNV2 kcnv2 (Catalog #AAA8242553) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kv8.2 Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Kv8.2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: (1/1000 - 1/2000); Immunohistochemistry: (1/100 - 1/200). Researchers should empirically determine the suitability of the KCNV2 kcnv2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kv8.2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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