Western Blot (WB)
(Western blot analysis of extracts from COS7, 293 and 3T3 cells, using KSR2 antibody.)
Rabbit anti-Human, Mouse KSR2 Polyclonal Antibody | anti-KSR2 antibody
KSR2 Antibody
IF: 1:100-1:500
Western Blot (WB)
(Western blot analysis of extracts from COS7, 293 and 3T3 cells, using KSR2 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from COS7, 293 and 3T3 cells, using KSR2 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells, using KSR2 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells, using KSR2 antibody.)
NCBI and Uniprot Product Information
Uniprot Description
KSR2: Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, TKL; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; TKL group; RAF family
Chromosomal Location of Human Ortholog: 12q24.22-q24.23
Cellular Component: membrane; cytoplasm
Molecular Function: protein serine/threonine kinase activity; metal ion binding; ATP binding
Biological Process: protein amino acid phosphorylation
Research Articles on KSR2
Similar Products
Product Notes
The KSR2 ksr2 (Catalog #AAA7132273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KSR2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KSR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:3000 IF: 1:100-1:500. Researchers should empirically determine the suitability of the KSR2 ksr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KSR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
