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Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using 2NF24 antibody.)

Rabbit anti-Human, Mouse KOX17/ZNF24 Polyclonal Antibody | anti-KOX17 antibody

KOX17/ZNF24 Polyclonal Antibody

Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
KOX17/ZNF24; Polyclonal Antibody; KOX17/ZNF24 Polyclonal Antibody; KOX17; Retinoic acid suppression protein A; RSG A; RSGA; Zfp191; Zinc finger and SCAN domain containing protein 3; Zinc finger protein 191; Zinc finger protein 24; Zinc finger protein KOX17; ZNF 24; ZNF191; ZSCAN 3; ZSCAN3; anti-KOX17 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
KOX17/ZNF24 polyclonal antibody detects endogenous levels of KOX17/ZNF24 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
368
Applicable Applications for anti-KOX17 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant full length Human KOX17/ZNF24.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using 2NF24 antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using 2NF24 antibody.)
Related Product Information for anti-KOX17 antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF191 (Zinc finger protein 191), also known as ZNF24, KOX17, ZSCAN3 or RSG-A, is a 368 amino acid nuclear protein that belongs to the Krueppel C2H2-type zinc-finger protein family. Expressed in tissues throughout the body with the exception of heart, ZNF191 functions as a transcriptional repressor for a variety of proteins, such as VEGF (vascular endothelial growth factor), and is thought to be important for early embryonic development and cell proliferation. ZNF191 contains four C2H2-type zinc fingers and one SCAN box domain and, upon DNA damage, may be phosphorylated by ATM or ATR.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 42kDa
NCBI Official Full Name
zinc finger protein 24 isoform 1
UniProt Protein Name
Zinc finger protein 24
UniProt Gene Name
ZNF24
UniProt Synonym Gene Names
KOX17; ZNF191; ZSCAN3; RSG-A
UniProt Entry Name
ZNF24_HUMAN

Uniprot Description

ZNF24: a probable transcriptional regulator of the krueppel C2H2-type zinc-finger protein family.

Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 18q12

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; DNA binding; zinc ion binding; sequence-specific DNA binding; transcription factor activity

Biological Process: myelination; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent

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Product Notes

The KOX17 znf24 (Catalog #AAA3012145) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KOX17/ZNF24 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KOX17/ZNF24 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the KOX17 znf24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KOX17/ZNF24, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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