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Rabbit anti-Human KMT5B Polyclonal Antibody | anti-KMT5B antibody

KMT5B Antibody, Biotin conjugated

Gene Names
KMT5B; CGI85; MRD51; CGI-85; SUV420H1
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
KMT5B; Polyclonal Antibody; KMT5B Antibody; Biotin conjugated; Histone-lysine N-methyltransferase KMT5BCurated; Lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B; anti-KMT5B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
370
Applicable Applications for anti-KMT5B antibody
ELISA (EIA)
Immunogen
Recombinant Human Histone-lysine N-methyltransferase KMT5B protein (100-150AA)
Conjugation
Biotin
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-KMT5B antibody
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
Product Categories/Family for anti-KMT5B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,959 Da
NCBI Official Full Name
histone-lysine N-methyltransferase KMT5B isoform 5
NCBI Official Synonym Full Names
lysine methyltransferase 5B
NCBI Official Symbol
KMT5B
NCBI Official Synonym Symbols
CGI85; MRD51; CGI-85; SUV420H1
NCBI Protein Information
histone-lysine N-methyltransferase KMT5B
UniProt Protein Name
Histone-lysine N-methyltransferase KMT5B
UniProt Gene Name
KMT5B
UniProt Synonym Gene Names
Su(var)4-20 homolog 1; Suv4-20h1

NCBI Description

This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Uniprot Description

Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.

Research Articles on KMT5B

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Product Notes

The KMT5B kmt5b (Catalog #AAA7105268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KMT5B Antibody, Biotin conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KMT5B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the KMT5B kmt5b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KMT5B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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