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Western Blot (WB) (Gel: 12%SDS-PAGE Lysate: 40 μ g Lane 1-4: K562£¬Jurkat£¬MCF-7 and 293T cell Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)

Rabbit anti-Human KLRC2 Polyclonal Antibody | anti-KLRC2 antibody

KLRC2 Antibody

Gene Names
KLRC2; NKG2C; CD159c; NKG2-C
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
KLRC2; Polyclonal Antibody; KLRC2 Antibody; NKG2C; CD159c; NKG2-C; anti-KLRC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total KLRC2 protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.8 mg/ml (varies by lot)
Sequence Length
231
Applicable Applications for anti-KLRC2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
Immunogen
Synthetic peptide of human KLRC2
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Gel: 12%SDS-PAGE Lysate: 40 μ g Lane 1-4: K562£¬Jurkat£¬MCF-7 and 293T cell Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)

Western Blot (WB) (Gel: 12%SDS-PAGE Lysate: 40 μ g Lane 1-4: K562£¬Jurkat£¬MCF-7 and 293T cell Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)
Related Product Information for anti-KLRC2 antibody
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain.
Product Categories/Family for anti-KLRC2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,072 Da
NCBI Official Full Name
NKG2-C type II integral membrane protein
NCBI Official Synonym Full Names
killer cell lectin like receptor C2
NCBI Official Symbol
KLRC2
NCBI Official Synonym Symbols
NKG2C; CD159c; NKG2-C
NCBI Protein Information
NKG2-C type II integral membrane protein
UniProt Protein Name
NKG2-C type II integral membrane protein
UniProt Gene Name
KLRC2
UniProt Synonym Gene Names
NKG2C
UniProt Entry Name
NKG2C_HUMAN

Uniprot Description

KLRC2: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: protein binding; transmembrane receptor activity

Biological Process: cellular defense response; innate immune response; natural killer cell mediated immunity; signal transduction

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Product Notes

The KLRC2 klrc2 (Catalog #AAA9415513) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLRC2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLRC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the KLRC2 klrc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLRC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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