Rabbit anti-Human, Mouse KLF7 Polyclonal Antibody | anti-KLF7 antibody
KLF7 Antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7123890(KLF7 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using MBS7123890(KLF7 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200))
SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-4: Humna colon cancer tissue, mouse kidney tissue, mouse testis tissue, human fetal brain tissue, Primary antibody: MBS7123890(KLF7 Antibody) at dilution 1/483.3, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Description
KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein type: DNA-binding; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 2q32
Cellular Component: nucleus
Molecular Function: DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; dendrite morphogenesis
Research Articles on KLF7
Similar Products
Product Notes
The KLF7 klf7 (Catalog #AAA7123890) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLF7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KLF7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the KLF7 klf7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLF7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.