Target Description: KLF2/Lung Kruppel-like factor (LKLF) functions as a negative regulator of adipocyte differentiation. KLF2 is highly expressed in adipose tissue, and studies in cell lines and primary cells demonstrate that KLF2 is expressed in preadipocytes but not mature adipocytes.
NCBI and Uniprot Product Information
Uniprot Description
KLF2: Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein type: DNA-binding; C2H2-type zinc finger protein
Cellular Component: nucleus
Molecular Function: protein binding; nucleic acid binding; DNA binding; sequence-specific DNA binding; metal ion binding; transcription factor activity
Biological Process: erythrocyte homeostasis; erythrocyte maturation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; in utero embryonic development; positive regulation of transcription, DNA-dependent; multicellular organism growth; negative regulation of interleukin-6 production; cell morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein metabolic process; regulation of gene expression, epigenetic
Research Articles on KLF2
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Product Notes
The KLF2 klf2 (Catalog #AAA3203792) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLF2 antibody - middle region reacts with Human, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KLF2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the KLF2 klf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: IPASGPRNPF PPPFGPGPSF GGPGPALHYG PPAPGAFGLF EDAAAAAAAL. It is sometimes possible for the material contained within the vial of "KLF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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