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Western Blot (WB) (Western blotAll lanes: KIZ antibody at 2.41 ug/ml+ Hela whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 76,63,70,74,60 kDaObserved band size: 75,50 kDa)

Rabbit anti-Human KIZ Polyclonal Antibody | anti-KIZ antibody

KIZ Antibody

Gene Names
KIZ; RP69; HT013; Kizuna; PLK1S1; C20orf19; NCRNA00153
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
KIZ; Polyclonal Antibody; KIZ Antibody; Centrosomal protein kizuna; Polo-like kinase 1 substrate 1; C20orf19; NCRNA00153; PLK1S1; HT013; anti-KIZ antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
570
Applicable Applications for anti-KIZ antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Centrosomal protein kizuna protein (N-240AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-85385 / sc-85386
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: KIZ antibody at 2.41 ug/ml+ Hela whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 76,63,70,74,60 kDaObserved band size: 75,50 kDa)

Western Blot (WB) (Western blotAll lanes: KIZ antibody at 2.41 ug/ml+ Hela whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 76,63,70,74,60 kDaObserved band size: 75,50 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung tissue using MBS7045267 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung tissue using MBS7045267 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045267 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045267 at dilution of 1:100)
Related Product Information for anti-KIZ antibody
Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59,243 Da
NCBI Official Full Name
centrosomal protein kizuna isoform 2
NCBI Official Synonym Full Names
kizuna centrosomal protein
NCBI Official Symbol
KIZ
NCBI Official Synonym Symbols
RP69; HT013; Kizuna; PLK1S1; C20orf19; NCRNA00153
NCBI Protein Information
centrosomal protein kizuna
UniProt Protein Name
Centrosomal protein kizuna
Protein Family
UniProt Gene Name
KIZ
UniProt Synonym Gene Names
C20orf19; NCRNA00153; PLK1S1
UniProt Entry Name
KIZ_HUMAN

NCBI Description

The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

Uniprot Description

Kizuna: a novel centrosomal protein that, along with the protein kinase Plk1, plays an important role in establishing the mitotic centrosomal architecture during spindle formation and maintaining spindle bipolarity. Its depletion causes centriolar instability during prometaphase which results in multipolar spindles. Four alternatively spliced human isoforms have been reported.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 20p11.23

Cellular Component: centrosome

Molecular Function: protein binding; protein kinase binding

Biological Process: spindle organization and biogenesis

Research Articles on KIZ

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Product Notes

The KIZ kiz (Catalog #AAA7045267) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KIZ Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KIZ can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the KIZ kiz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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