Western Blot (WB)
(Western Blot analysis of KISS1 expression in transfected 293T cell line by KISS1 polyclonal antibody. Lane 1: KISS1 transfected lysate (14.7kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human KISS1 Polyclonal Antibody | anti-KISS1 antibody
KISS1 (Metastasis-suppressor KiSS-1, Kisspeptin-1, Metastin, PP5098, MGC39258) (Biotin)
Gene Names
KISS1; HH13; KiSS-1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
KISS1; Polyclonal Antibody; KISS1 (Metastasis-suppressor KiSS-1; Kisspeptin-1; Metastin; PP5098; MGC39258) (Biotin); anti-KISS1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human KISS1.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Sequence Length
726
Applicable Applications for anti-KISS1 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human KISS1, aa1-138 (NP_002247.3).
Immunogen Sequence
MNSLVSWQLLLFLCATHFGEPLEKVASVGNSRPTGQQLESLGLLAPGEQSLPCTERKPAATARLSRRGTSLSPPPESSGSPQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRFGKREAAPGNHGRSAGRG
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of KISS1 expression in transfected 293T cell line by KISS1 polyclonal antibody. Lane 1: KISS1 transfected lysate (14.7kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of KISS1 expression in transfected 293T cell line by KISS1 polyclonal antibody. Lane 1: KISS1 transfected lysate (14.7kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-KISS1 antibody
KiSS-1 has been reported to suppress metastases of melanomas and breast carcinomas without affecting tumorigenicity. Human KiSS-1 transcripts are predominately expressed in the brain and placenta. Expression of KiSS-1 reduces the level of NFkB p50/p65 binding to the MMP9 promoter and correlates with diminished expression of the 92kD type IV collagenase (MMP-9). KiSS-1 may regulate events downstream of cell-matrix adhesion in mechanisms involving cytoskeletal reorganization.
Product Categories/Family for anti-KISS1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Homo sapiens KiSS-1 metastasis-suppressor, mRNA
NCBI Official Synonym Full Names
KiSS-1 metastasis suppressor
NCBI Official Symbol
KISS1
NCBI Official Synonym Symbols
HH13; KiSS-1
NCBI Protein Information
metastasis-suppressor KiSS-1
Protein Family
NCBI Description
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]
Research Articles on KISS1
Similar Products
Product Notes
The KISS1 (Catalog #AAA6383643) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KISS1 (Metastasis-suppressor KiSS-1, Kisspeptin-1, Metastin, PP5098, MGC39258) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KISS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KISS1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KISS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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