Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using KIF2C Polyclonal Antibody at dilution of 1:70(×200))
Rabbit KIF2C Polyclonal Antibody | anti-KIF2C antibody
KIF2C Polyclonal Antibody
ELISA: 1:5000-1:10000
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using KIF2C Polyclonal Antibody at dilution of 1:70(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using KIF2C Polyclonal Antibody at dilution of 1:70(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using KIF2C Polyclonal Antibody at dilution of 1:70(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using KIF2C Polyclonal Antibody at dilution of 1:70(×200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Uniprot Description
KIF2C: In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cancer Testis Antigen (CTA); Microtubule-binding; Motor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: kinetochore; microtubule cytoskeleton; kinesin complex; membrane; cytoplasmic microtubule; cytosol; nucleus; chromosome, pericentric region
Molecular Function: centromeric DNA binding; microtubule plus-end binding; protein binding; ATPase activity; microtubule motor activity; ATP binding
Biological Process: mitosis; cell proliferation; cell division; metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule depolymerization; regulation of chromosome segregation; mitotic cell cycle; blood coagulation; mitotic metaphase plate congression; microtubule-based movement; establishment and/or maintenance of microtubule cytoskeleton polarity
Research Articles on KIF2C
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Product Notes
The KIF2C kif2c (Catalog #AAA2560639) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KIF2C Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KIF2C can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:200 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the KIF2C kif2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF2C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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